Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1844389..1844875 Replicon chromosome
Accession NZ_CP116393
Organism Streptococcus suis strain SS/UPM/MY/F001

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PFZ59_RS09295 Protein ID WP_024410064.1
Coordinates 1844618..1844875 (+) Length 86 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PFZ59_RS09290 Protein ID WP_208572645.1
Coordinates 1844389..1844628 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PFZ59_RS09265 (PFZ59_09265) 1839573..1840739 + 1167 WP_208582215.1 ATP-grasp domain-containing protein -
PFZ59_RS09270 (PFZ59_09270) 1840880..1841020 + 141 WP_032513066.1 hypothetical protein -
PFZ59_RS09275 (PFZ59_09275) 1841033..1841422 + 390 WP_208582214.1 NisI/SpaI family lantibiotic immunity lipoprotein -
PFZ59_RS09280 (PFZ59_09280) 1841431..1842183 + 753 WP_024407069.1 ABC transporter ATP-binding protein -
PFZ59_RS09285 (PFZ59_09285) 1842184..1844154 + 1971 WP_208582211.1 ABC transporter permease -
PFZ59_RS09290 (PFZ59_09290) 1844389..1844628 + 240 WP_208572645.1 DUF6290 family protein Antitoxin
PFZ59_RS09295 (PFZ59_09295) 1844618..1844875 + 258 WP_024410064.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PFZ59_RS09300 (PFZ59_09300) 1844914..1845582 + 669 WP_208582667.1 response regulator transcription factor -
PFZ59_RS09305 (PFZ59_09305) 1845579..1846520 + 942 WP_208582669.1 sensor histidine kinase -
PFZ59_RS09310 (PFZ59_09310) 1846697..1848205 + 1509 WP_208582671.1 phosphomannomutase/phosphoglucomutase -
PFZ59_RS09315 (PFZ59_09315) 1848269..1849339 - 1071 WP_044683310.1 tyrosine recombinase XerS -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1777388..1911392 134004


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-75)

Antitoxin

Protein of unknown function DUF6290

(1-75)


Sequences

Toxin        


Download         Length: 86 a.a.        Molecular weight: 9836.52 Da        Isoelectric Point: 10.7134

>T268633 WP_024410064.1 NZ_CP116393:1844618-1844875 [Streptococcus suis]
MSYKVILSAKAQKQIRKMDKTAASLILRYLYKHIDGCDNPRQYGKALTANRSGQWRYRIGNYRVIVSIEDDKLILTSLKM
RNGSI

Download         Length: 258 bp

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8907.14 Da        Isoelectric Point: 3.7832

>AT268633 WP_208572645.1 NZ_CP116393:1844389-1844628 [Streptococcus suis]
MAAITLKVSEQDKLFMQAMAKFEGVSLSELIRTKTLEALEDEYDARVADIAWVEYQEDLANGIEPITLEQMAEELGIEL

Download         Length: 240 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References