Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 448706..449359 Replicon chromosome
Accession NZ_CP116387
Organism Acinetobacter baumannii strain WM98

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag PIG43_RS02170 Protein ID WP_000931890.1
Coordinates 448970..449359 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag PIG43_RS02165 Protein ID WP_001288210.1
Coordinates 448706..448963 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIG43_RS02145 (PIG43_02145) 444222..445229 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
PIG43_RS02150 (PIG43_02150) 445248..445625 + 378 WP_001216380.1 50S ribosomal protein L17 -
PIG43_RS02155 (PIG43_02155) 445806..447296 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
PIG43_RS02160 (PIG43_02160) 447346..448518 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
PIG43_RS02165 (PIG43_02165) 448706..448963 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
PIG43_RS02170 (PIG43_02170) 448970..449359 + 390 WP_000931890.1 membrane protein Toxin
PIG43_RS02175 (PIG43_02175) 450129..451214 + 1086 WP_000049106.1 hypothetical protein -
PIG43_RS02180 (PIG43_02180) 451292..451858 + 567 WP_000651536.1 rhombosortase -
PIG43_RS02185 (PIG43_02185) 452046..454241 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T268626 WP_000931890.1 NZ_CP116387:448970-449359 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT268626 WP_001288210.1 NZ_CP116387:448706-448963 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References