Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 376721..377237 Replicon chromosome
Accession NZ_CP116384
Organism Vibrio sp. SCSIO 43137

Toxin (Protein)


Gene name relB Uniprot ID -
Locus tag PK654_RS17480 Protein ID WP_271700320.1
Coordinates 376968..377237 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag PK654_RS17475 Protein ID WP_271700319.1
Coordinates 376721..376975 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PK654_RS17460 (PK654_17460) 372790..374043 + 1254 WP_271700316.1 aromatic amino acid transport family protein -
PK654_RS17465 (PK654_17465) 374138..375499 + 1362 WP_271700317.1 L-serine ammonia-lyase -
PK654_RS17470 (PK654_17470) 375850..376629 + 780 WP_271700318.1 class I SAM-dependent methyltransferase -
PK654_RS17475 (PK654_17475) 376721..376975 + 255 WP_271700319.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PK654_RS17480 (PK654_17480) 376968..377237 + 270 WP_271700320.1 Txe/YoeB family addiction module toxin Toxin
PK654_RS17485 (PK654_17485) 377455..378297 + 843 WP_271700322.1 ion transporter -
PK654_RS17490 (PK654_17490) 378662..379684 - 1023 WP_271700324.1 tryptophan--tRNA ligase -
PK654_RS17495 (PK654_17495) 380341..382098 + 1758 WP_271700325.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 374138..384728 10590


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10726.15 Da        Isoelectric Point: 8.8576

>T268622 WP_271700320.1 NZ_CP116384:376968-377237 [Vibrio sp. SCSIO 43137]
MSSRQRLLSWTDDAWDDYLYWQTQDKKTLKRINKLINDVKRSPFEGIGKPEPLKENLSGFWSRRIDDTNRLVYVVDEQAI
TIISCRYHY

Download         Length: 270 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9511.64 Da        Isoelectric Point: 4.7914

>AT268622 WP_271700319.1 NZ_CP116384:376721-376975 [Vibrio sp. SCSIO 43137]
MRIVSFTEARNGLKAVLDGVVNDADTTVITRRDSEDAVVMSLDYYNSLMETVHLLRSPQNAEHLNRSIEQYRAGKTTARE
LIDE

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References