268621

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 1886688..1887454 Replicon chromosome
Accession NZ_CP116383
Organism Vibrio sp. SCSIO 43137

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PK654_RS08810 Protein ID WP_271695207.1
Coordinates 1886688..1887185 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PK654_RS08815 Protein ID WP_271695209.1
Coordinates 1887182..1887454 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PK654_RS08780 (PK654_08780) 1881877..1882116 + 240 WP_271695198.1 RNA-binding protein -
PK654_RS08785 (PK654_08785) 1882163..1882993 - 831 WP_271695199.1 hypothetical protein -
PK654_RS08790 (PK654_08790) 1883129..1883647 - 519 WP_271695200.1 GNAT family N-acetyltransferase -
PK654_RS08795 (PK654_08795) 1883941..1884858 - 918 WP_271695202.1 AraC family transcriptional regulator -
PK654_RS08800 (PK654_08800) 1885177..1885575 + 399 WP_271695204.1 hypothetical protein -
PK654_RS08805 (PK654_08805) 1885619..1886548 + 930 WP_271695205.1 alpha/beta hydrolase -
PK654_RS08810 (PK654_08810) 1886688..1887185 - 498 WP_271695207.1 GNAT family N-acetyltransferase Toxin
PK654_RS08815 (PK654_08815) 1887182..1887454 - 273 WP_271695209.1 DUF1778 domain-containing protein Antitoxin
PK654_RS08820 (PK654_08820) 1887895..1888344 - 450 WP_271695211.1 Cd(II)/Pb(II)-responsive transcriptional regulator -
PK654_RS08825 (PK654_08825) 1888467..1888988 + 522 WP_271695213.1 disulfide bond formation protein B -
PK654_RS08830 (PK654_08830) 1888975..1889607 + 633 WP_271695215.1 thioredoxin domain-containing protein -
PK654_RS08835 (PK654_08835) 1889902..1890126 - 225 WP_271695216.1 VF530 family protein -
PK654_RS08840 (PK654_08840) 1890424..1890933 + 510 WP_271695217.1 hypothetical protein -
PK654_RS08845 (PK654_08845) 1890930..1891532 - 603 WP_271695219.1 methyltransferase domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(86-147)

Antitoxin

Vibrio phage ICP1, Orf50

(7-85)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 18520.33 Da        Isoelectric Point: 9.5422

>T268621 WP_271695207.1 NZ_CP116383:c1887185-1886688 [Vibrio sp. SCSIO 43137]
MMNTVLLDKAKHDRNRFNCGIDALNNHLKVMASQQAKKDNSRTFVLEDDNNNSYIVGFYTLTMAPIDLKALPDKLQKMHQ
SSTSGGLIARLVVDERYKGKGLGEWLLIDALRKLLAASDSVAFPIVIVDAKDGAKQFYERYGFKAFQYAENKLFITISDV
RASLA

Download         Length: 498 bp

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 9636.93 Da        Isoelectric Point: 4.5557

>AT268621 WP_271695209.1 NZ_CP116383:c1887454-1887182 [Vibrio sp. SCSIO 43137]
MATTLPRITARVDVDTQDLLTKAAAIAGTSSINSFVLSAAIEKAKQVIEREQALKLSEADAMLLMEALDSPAEANSNLKA
ASDRYENKTQ

Download         Length: 273 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References