Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3666223..3666866 Replicon chromosome
Accession NZ_CP116340
Organism Pseudomonas sp. JBR1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PJ259_RS16990 Protein ID WP_271653593.1
Coordinates 3666453..3666866 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PJ259_RS16985 Protein ID WP_271653592.1
Coordinates 3666223..3666453 (+) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJ259_RS16965 (PJ259_16965) 3661457..3661873 - 417 WP_271653588.1 organic hydroperoxide resistance protein -
PJ259_RS16970 (PJ259_16970) 3662019..3662453 - 435 WP_271653589.1 MarR family transcriptional regulator -
PJ259_RS16975 (PJ259_16975) 3662541..3664058 + 1518 WP_271653590.1 sigma-54-dependent transcriptional regulator -
PJ259_RS16980 (PJ259_16980) 3664206..3665930 - 1725 WP_271653591.1 ubiquinone-dependent pyruvate dehydrogenase -
PJ259_RS16985 (PJ259_16985) 3666223..3666453 + 231 WP_271653592.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
PJ259_RS16990 (PJ259_16990) 3666453..3666866 + 414 WP_271653593.1 tRNA(fMet)-specific endonuclease VapC Toxin
PJ259_RS16995 (PJ259_16995) 3667168..3667536 + 369 WP_271653594.1 glycine cleavage system protein GcvH -
PJ259_RS17000 (PJ259_17000) 3667544..3670399 + 2856 WP_271653595.1 aminomethyl-transferring glycine dehydrogenase -
PJ259_RS17005 (PJ259_17005) 3670659..3671768 + 1110 WP_271653596.1 glycine cleavage system aminomethyltransferase GcvT -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-124)

Antitoxin

SpoVT-AbrB domain

(7-35)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15256.51 Da        Isoelectric Point: 7.9082

>T268600 WP_271653593.1 NZ_CP116340:3666453-3666866 [Pseudomonas sp. JBR1]
MLKFMLDTNTCIFTIKNRPESVREAFTRHHGQLCISTVTLMELIYGAEKSSSPERNLAVVEGFAARLEVLKYGLEAAAHT
GQLRAELARAGQQIGPYDQMIAGHARSLGLIVVTNNRREFDRVPGLRVEDWVTAEKG

Download         Length: 414 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8431.36 Da        Isoelectric Point: 4.4013

>AT268600 WP_271653592.1 NZ_CP116340:3666223-3666453 [Pseudomonas sp. JBR1]
VEQGAVFQSNRSQAVRLPKAVALPEDVKRVDVVVVGRARIITPTGESWNSWFEGEGVTADFMAERDQPAEQDREGF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References