Detailed information of TA system
Overview
TA module
| Type | III | Classification (family/domain) | toxIN/ToxN(toxin) |
| Location | 30058..30800 | Replicon | plasmid pBLB1_81 |
| Accession | NZ_CP116334 | ||
| Organism | Bacillus thuringiensis strain BLB1 | ||
Toxin (Protein)
| Gene name | toxN | Uniprot ID | - |
| Locus tag | PJW01_RS32670 | Protein ID | WP_016097319.1 |
| Coordinates | 30058..30642 (-) | Length | 195 a.a. |
Antitoxin (RNA)
| Gene name | toxI | ||
| Locus tag | - | ||
| Coordinates | 30704..30800 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PJW01_RS32650 (25464) | 25464..25910 | - | 447 | WP_016097323.1 | CPBP family intramembrane metalloprotease | - |
| PJW01_RS32655 (25940) | 25940..28081 | - | 2142 | WP_016097322.1 | type IA DNA topoisomerase | - |
| PJW01_RS32660 (28202) | 28202..28582 | - | 381 | WP_016097321.1 | hypothetical protein | - |
| PJW01_RS32665 (28689) | 28689..29990 | - | 1302 | WP_016097320.1 | hypothetical protein | - |
| PJW01_RS32670 (30058) | 30058..30642 | - | 585 | WP_016097319.1 | type III toxin-antitoxin system ToxN/AbiQ family toxin | Toxin |
| - (30704) | 30704..30800 | - | 97 | NuclAT_0 | - | Antitoxin |
| - (30704) | 30704..30800 | - | 97 | NuclAT_0 | - | Antitoxin |
| - (30704) | 30704..30800 | - | 97 | NuclAT_0 | - | Antitoxin |
| - (30704) | 30704..30800 | - | 97 | NuclAT_0 | - | Antitoxin |
| PJW01_RS32675 (30893) | 30893..31918 | - | 1026 | WP_016097318.1 | DUF3991 and TOPRIM domain-containing protein | - |
| PJW01_RS32680 (31998) | 31998..32549 | - | 552 | WP_016097317.1 | metal-dependent hydrolase | - |
| PJW01_RS32685 (32571) | 32571..33557 | - | 987 | WP_016097316.1 | hypothetical protein | - |
| PJW01_RS32690 (33619) | 33619..35250 | - | 1632 | WP_016097315.1 | ArdC-like ssDNA-binding domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Non-Mobilizable plasmid | - | - | 1..80698 | 80698 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 195 a.a. Molecular weight: 22900.17 Da Isoelectric Point: 8.9694
>T268595 WP_016097319.1 NZ_CP116334:c30642-30058 [Bacillus thuringiensis]
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER
MANKDNPKFYTISTEYIDYLRETDSKVPFNKDEQHSRPYVGVLEKINGHDYFVPLTSRNDKNFNSQVSVKLFDTDEKRIG
VLLVNNMIPVPEKECKEIDIAEKTAADPQYGNLMLKQYLFLKENMDRVTNKVEKVYKDVTVQGKPSHKQKFLKGVCCDFP
KLEEKCQEYKERDQAKERDKARRIAYMRQMGRER
Download Length: 585 bp
Antitoxin
Download Length: 97 bp
>AT268595 NZ_CP116334:c30800-30704 [Bacillus thuringiensis]
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA
GTAACCTTACTTTAGTAGGTGCGAAAAAATTGGTGTAACTCTACCGTAGTGAGTACCAAAAAATTGGTGTAGCCTTACCG
TAGTAGGCGCTAAAAAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
