268585

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4560125..4560486 Replicon chromosome
Accession NZ_CP116305
Organism Xanthomonas perforans strain GEV872

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag PJW04_RS19940 Protein ID WP_005914328.1
Coordinates 4560125..4560259 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID A0A0G8WVL8
Locus tag PJW04_RS19945 Protein ID WP_008576433.1
Coordinates 4560334..4560486 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJW04_RS19925 (PJW04_19925) 4557159..4558103 - 945 WP_008576427.1 MBL fold metallo-hydrolase -
PJW04_RS19930 (PJW04_19930) 4558232..4559521 - 1290 WP_008576429.1 tryptophan--tRNA ligase -
PJW04_RS19935 (PJW04_19935) 4559688..4559897 - 210 WP_003486601.1 CsbD family protein -
PJW04_RS19940 (PJW04_19940) 4560125..4560259 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
PJW04_RS19945 (PJW04_19945) 4560334..4560486 - 153 WP_008576433.1 entericidin A/B family lipoprotein Antitoxin
PJW04_RS19950 (PJW04_19950) 4560593..4561516 - 924 WP_008576436.1 arginase -
PJW04_RS19955 (PJW04_19955) 4561837..4562289 + 453 WP_008576438.1 roadblock/LC7 domain-containing protein -
PJW04_RS19960 (PJW04_19960) 4562353..4562712 + 360 WP_003486613.1 hypothetical protein -
PJW04_RS19965 (PJW04_19965) 4562809..4563726 + 918 WP_008576439.1 hypothetical protein -
PJW04_RS19970 (PJW04_19970) 4563723..4564265 + 543 WP_003486615.1 GTPase -
PJW04_RS19975 (PJW04_19975) 4564734..4565414 + 681 WP_008576441.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T268585 WP_005914328.1 NZ_CP116305:c4560259-4560125 [Xanthomonas perforans]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5137.08 Da        Isoelectric Point: 8.2782

>AT268585 WP_008576433.1 NZ_CP116305:c4560486-4560334 [Xanthomonas perforans]
MKRLLTLMVLALFSAGVMTGCNTVAGAGKDMQGAGDKVEKTAEKCSDGKC

Download         Length: 153 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A0G8WVL8

References