Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 69354..69901 Replicon chromosome
Accession NZ_CP116305
Organism Xanthomonas perforans strain GEV872

Toxin (Protein)


Gene name relE Uniprot ID A0A0G9C4Q2
Locus tag PJW04_RS00275 Protein ID WP_008574054.1
Coordinates 69599..69901 (+) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q3BZM5
Locus tag PJW04_RS00270 Protein ID WP_008574056.1
Coordinates 69354..69611 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJW04_RS00255 (PJW04_00255) 64499..65956 - 1458 WP_008574059.1 ribonuclease H-like domain-containing protein -
PJW04_RS00260 (PJW04_00260) 65953..68448 - 2496 WP_046932047.1 DEAD/DEAH box helicase -
PJW04_RS00265 (PJW04_00265) 68626..69288 + 663 WP_008574057.1 hemolysin III family protein -
PJW04_RS00270 (PJW04_00270) 69354..69611 + 258 WP_008574056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
PJW04_RS00275 (PJW04_00275) 69599..69901 + 303 WP_008574054.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PJW04_RS00285 (PJW04_00285) 70083..70982 - 900 WP_008574052.1 SDR family NAD(P)-dependent oxidoreductase -
PJW04_RS00290 (PJW04_00290) 71042..71779 - 738 WP_008574050.1 SDR family oxidoreductase -
PJW04_RS00295 (PJW04_00295) 71905..72816 + 912 WP_033478804.1 LysR family transcriptional regulator -
PJW04_RS00300 (PJW04_00300) 73016..73726 + 711 WP_008574047.1 hypothetical protein -
PJW04_RS00305 (PJW04_00305) 73964..74572 - 609 WP_008574046.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11522.33 Da        Isoelectric Point: 9.1267

>T268584 WP_008574054.1 NZ_CP116305:69599-69901 [Xanthomonas perforans]
MAEIIWSVPALADLDAIADDIAIDNAPAAAAALVKWVLPQVERLIEHPDSGSRPQELQRSRYRQIVEPPCRVFYRVDGQR
IVLVHVMRWERALRRNRLSR

Download         Length: 303 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9686.18 Da        Isoelectric Point: 10.0780

>AT268584 WP_008574056.1 NZ_CP116305:69354-69611 [Xanthomonas perforans]
MRTELVTTLKRQATEPLAAAERDKEPILITQHGLPRAYVVDVASDERMQQRIALLEGIARGEMAVAQGRTLRHEQAQQHM
ARWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0G9C4Q2

Antitoxin

Source ID Structure
AlphaFold DB A0A3G2WGS6

References