Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 4179166..4180861 Replicon chromosome
Accession NZ_CP116304
Organism Pseudomonas sp. Q1-7

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PJW05_RS19370 Protein ID WP_271408590.1
Coordinates 4179992..4180861 (-) Length 290 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PJW05_RS19365 Protein ID WP_271408589.1
Coordinates 4179166..4179999 (-) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PJW05_RS19345 4174397..4175881 - 1485 WP_271408585.1 aldehyde dehydrogenase -
PJW05_RS19350 4175893..4176696 - 804 WP_271408586.1 aspartate dehydrogenase -
PJW05_RS19355 4176707..4178389 - 1683 WP_271408587.1 thiamine pyrophosphate-binding protein -
PJW05_RS19360 4178382..4179179 - 798 WP_271408588.1 SDR family oxidoreductase -
PJW05_RS19365 4179166..4179999 - 834 WP_271408589.1 IclR family transcriptional regulator Antitoxin
PJW05_RS19370 4179992..4180861 - 870 WP_271408590.1 alpha/beta fold hydrolase Toxin
PJW05_RS19375 4180870..4181400 - 531 WP_271408591.1 cupin domain-containing protein -
PJW05_RS19380 4181414..4182175 - 762 WP_271408592.1 SDR family oxidoreductase -
PJW05_RS19385 4182181..4182957 - 777 WP_271408593.1 ABC transporter permease -
PJW05_RS19390 4182967..4183962 - 996 WP_271408594.1 ABC transporter substrate-binding protein -
PJW05_RS19395 4184000..4184851 - 852 WP_271408595.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(41-272)

Antitoxin

Transcription regulator IclR, N-terminal

(16-64)


Sequences

Toxin        


Download         Length: 290 a.a.        Molecular weight: 30401.85 Da        Isoelectric Point: 7.1910

>T268583 WP_271408590.1 NZ_CP116304:c4180861-4179992 [Pseudomonas sp. Q1-7]
MNMAQTHIPAPSLQQCFPERLVPLADGARVAIRECGQGPVVVLLHGIGSGSASWLHCAQRLAAGNRVIAWDAPGYGLSTP
LPQARPKAADYAMRLELLLDALGVDSCLLVGHSLGALMATAYAAGIGAARVRRLVLLSPARGYGAEELRDIGAQVRRQRL
DNLERLGIDGMASERTARLLGRRPSEDALAWVRWNMARLNPGGYRQAVELLCGDDLLGHGVPVAPCEVHCGEDDGITTPQ
ACGAIAHLLGASFSLIPGAGHASPIEQPEVVAGRIGHAQRHSLEGTANG

Download         Length: 870 bp

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 31063.53 Da        Isoelectric Point: 6.3887

>AT268583 WP_271408589.1 NZ_CP116304:c4179999-4179166 [Pseudomonas sp. Q1-7]
MDKPDDQQDKYIVPGLERGLLLLCEFSRKNRTLSAPELARRLKLPRSTIFRLLTTLETMGFVNRIGNEYRLGMSVLRLGF
EYLASLELTELGQPLLNRLCDDIRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVFGRILLQDLSLGELR
ELYPEEHLEQFSPNTPKTVLELFDLVQGDRQRGFVQGEGFFESTISTVAAPVRDHSGKVVAAMGATIPSAHIEPVRIDSL
VYSVRDSADELSHLLNYTPDSHDNVTSIFRSKQHEPV

Download         Length: 834 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References