Detailed information of TA system TA268581

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /Acetyltransf_4(toxin)
• Location: 1551568..1552983
• Replicon: chromosome
• Accession: NZ_CP116304
• Organism: Pseudomonas sp. Q1-7

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PJW05_RS07175
• Protein ID: WP_271411029.1
• Coordinates: 1551568..1552137 (+)
• Length: 190 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: PJW05_RS07180
• Protein ID: WP_271411030.1
• Coordinates: 1552141..1552983 (+)
• Length: 281 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PJW05_RS07165	1547194..1547613	+	420	WP_271412186.1	hypothetical protein	-
PJW05_RS07170	1547838..1551317	-	3480	WP_271411028.1	PAS domain-containing hybrid sensor histidine kinase/response regulator	-
PJW05_RS07175	1551568..1552137	+	570	WP_271411029.1	GNAT family protein	Toxin
PJW05_RS07180	1552141..1552983	+	843	WP_271411030.1	AraC family transcriptional regulator	Antitoxin
PJW05_RS07185	1553020..1553751	+	732	WP_271411031.1	AzlC family ABC transporter permease	-
PJW05_RS07190	1553733..1554062	+	330	WP_271411032.1	AzlD domain-containing protein	-
PJW05_RS07195	1554269..1556143	+	1875	WP_271411033.1	MFS transporter	-
PJW05_RS07200	1556185..1556499	-	315	WP_271411034.1	quaternary ammonium compound efflux SMR transporter SugE	-
PJW05_RS07205	1556643..1557593	-	951	WP_271411035.1	bile acid:sodium symporter family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (14-146)

Antitoxin

• AraC-type arabinose-binding/dimerisation domain (19-151)

Sequences

Toxin

Protein

• Length: 190 a.a.
• Molecular weight: 21155.16 Da
• Isoelectric Point: 7.3198

>T268581 WP_271411029.1 NZ_CP116304:1551568-1552137 [Pseudomonas sp. Q1-7]
MFNPQPVTLQRGALRLDPLVEADIPPLVTLAEANREALAYMNGPLRPDWYRQGLAAQRDGQAVVFAIRLGDNLVGTTRFA
DFLPSLPAAEIGWTWLAAGEHGSGLNASIKYLMLRHAFEEWQLVRVELKTAASNLRAQRAIEKLGAQREGVLRNHRRLAD
GRLDDSVLYSITDRDWPDVKQRLEALFSA

Nucleotide

• Length: 570 bp

Antitoxin

Protein

• Length: 281 a.a.
• Molecular weight: 31282.62 Da
• Isoelectric Point: 8.0610

>AT268581 WP_271411030.1 NZ_CP116304:1552141-1552983 [Pseudomonas sp. Q1-7]
MGEPREDAHFWQAGHLDGLELLSARYIEHRFAPHVHDGYVIAVLEAGAERYRYRGVEHLAGAGSLALINPDEVHTGSKGH
DEGWRYRVFYPDIALVRGALDELELPLAGMPAFIGSVHRDPDLVRWFVNLHRLLEGEASALEQQTAWREALLALFRRHSK
LPEPGLPGREPLAVLRAKDLLRERLAEPPSLEALAAEVRLSPFHFARTFRRATGLPPHAWLKQQRLDQARALLKAGCAPA
GVAAQLGFADQSHLTRQFKQAYGVGPGEYRNACARSFKTH

Nucleotide

• Length: 843 bp