Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 3434..3911 Replicon plasmid pASal3_J225
Accession NZ_CP116262
Organism Aeromonas salmonicida subsp. salmonicida strain J225

Toxin (Protein)


Gene name relE Uniprot ID A0A8T8CMR8
Locus tag PI860_RS23310 Protein ID WP_073531821.1
Coordinates 3434..3703 (-) Length 90 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID Q7X2E4
Locus tag PI860_RS23315 Protein ID WP_005321784.1
Coordinates 3687..3911 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PI860_RS23290 (PI860_23305) 75..485 - 411 WP_005321773.1 MobC family plasmid mobilization relaxosome protein -
PI860_RS23295 (PI860_23310) 696..1019 + 324 WP_005321770.1 hypothetical protein -
PI860_RS23300 (PI860_23315) 1134..2120 - 987 WP_005321767.1 replication initiation protein -
PI860_RS23305 (PI860_23320) 2696..3325 - 630 WP_005321764.1 hypothetical protein -
PI860_RS23310 (PI860_23325) 3434..3703 - 270 WP_073531821.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PI860_RS23315 (PI860_23330) 3687..3911 - 225 WP_005321784.1 TraY domain-containing protein Antitoxin
PI860_RS23320 (PI860_23335) 5693..6109 - 417 WP_005321738.1 MobC family plasmid mobilization relaxosome protein -
PI860_RS23325 (PI860_23340) 6321..6644 + 324 WP_005321740.1 hypothetical protein -
PI860_RS23330 (PI860_23345) 6758..7732 - 975 WP_005321745.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - aopP 1..10346 10346


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10358.02 Da        Isoelectric Point: 10.3800

>T268569 WP_073531821.1 NZ_CP116262:c3703-3434 [Aeromonas salmonicida subsp. salmonicida]
MAWKVELTDTAKKQLARLDKTQSQRITKYLRRIMMLENPRDAGKALTGNLRTYWRYRVGDYRVVCDIRDNDLVIVAVIIG
HRSEVYGGS

Download         Length: 270 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8686.77 Da        Isoelectric Point: 4.2712

>AT268569 WP_005321784.1 NZ_CP116262:c3911-3687 [Aeromonas salmonicida subsp. salmonicida]
MLAIRLPSEIEERLANLAQETGRTKTFYAREAILTHLEELEDYYLAERVMENVRKGEERLFSLDDVERDLGLES

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A151KEE9

References