Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 3869905..3870584 Replicon chromosome
Accession NZ_CP116249
Organism Enterobacter roggenkampii strain 120063

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag KK030_RS19235 Protein ID WP_016246873.1
Coordinates 3870243..3870584 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag KK030_RS19230 Protein ID WP_113372912.1
Coordinates 3869905..3870222 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
KK030_RS19190 (KK030_19150) 3864925..3865668 + 744 WP_214575118.1 hypothetical protein -
KK030_RS19200 (KK030_19160) 3866569..3867429 + 861 WP_214575113.1 GTPase family protein -
KK030_RS19205 (KK030_19165) 3867518..3868339 + 822 WP_113372767.1 DUF932 domain-containing protein -
KK030_RS19210 (KK030_19170) 3868363..3868602 + 240 WP_007869725.1 DUF905 domain-containing protein -
KK030_RS19215 (KK030_19175) 3868706..3869164 + 459 WP_113372854.1 antirestriction protein -
KK030_RS19220 (KK030_19180) 3869180..3869656 + 477 WP_000811693.1 RadC family protein -
KK030_RS19225 (KK030_19185) 3869665..3869886 + 222 WP_063841895.1 DUF987 domain-containing protein -
KK030_RS19230 (KK030_19190) 3869905..3870222 + 318 WP_113372912.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
KK030_RS19235 (KK030_19195) 3870243..3870584 + 342 WP_016246873.1 TA system toxin CbtA family protein Toxin
KK030_RS19245 (KK030_19205) 3871153..3872406 - 1254 WP_045354384.1 glutamate-5-semialdehyde dehydrogenase -
KK030_RS19250 (KK030_19210) 3872418..3873521 - 1104 WP_214574768.1 glutamate 5-kinase -
KK030_RS19255 (KK030_19215) 3873826..3874878 + 1053 WP_008501878.1 phosphoporin PhoE -
KK030_RS19260 (KK030_19220) 3875015..3875416 - 402 WP_008500249.1 sigma factor-binding protein Crl -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 3862348..3870584 8236


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-112)

Antitoxin

Antitoxin CbeA

(5-104)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12987.05 Da        Isoelectric Point: 10.2764

>T268560 WP_016246873.1 NZ_CP116249:3870243-3870584 [Enterobacter roggenkampii]
MKTLPATTQRAAKPCLAPVAVWQMLLTRLLKQHYGLTLNDTPFSEERVIQEHIDAGITLADAVNFLVEKYELVRIDRKGF
NWQEQSPYLRAVDILRARQATGLLRQSRNNVVR

Download         Length: 342 bp

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11847.42 Da        Isoelectric Point: 6.7339

>AT268560 WP_113372912.1 NZ_CP116249:3869905-3870222 [Enterobacter roggenkampii]
MSNITWGLQRDITPRLGARLVQEGNRLHYLADRASITGKFSDVECRKLDETCPHFIRHMESMLTTGELSPQHAHCVTLYH
NGFTCEADTLGSCGYVYIAIYPTQS

Download         Length: 318 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References