Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /Xre(antitoxin)
Location 5307941..5309101 Replicon chromosome
Accession NZ_CP116239
Organism Pseudomonas sp. TUM22785

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag PI990_RS23950 Protein ID WP_271658682.1
Coordinates 5307941..5308693 (-) Length 251 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag PI990_RS23955 Protein ID WP_021221398.1
Coordinates 5308730..5309101 (-) Length 124 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PI990_RS23930 (PI990_23930) 5303650..5304534 + 885 WP_043243092.1 metal-dependent hydrolase -
PI990_RS23935 (PI990_23935) 5304590..5305951 - 1362 WP_271661348.1 DNA recombination protein RmuC -
PI990_RS23940 (PI990_23940) 5306118..5306525 - 408 WP_021221395.1 SEL1-like repeat protein -
PI990_RS23945 (PI990_23945) 5306874..5307929 - 1056 WP_271658681.1 AraC family transcriptional regulator -
PI990_RS23950 (PI990_23950) 5307941..5308693 - 753 WP_271658682.1 RES family NAD+ phosphorylase Toxin
PI990_RS23955 (PI990_23955) 5308730..5309101 - 372 WP_021221398.1 DUF2384 domain-containing protein Antitoxin
PI990_RS23960 (PI990_23960) 5309225..5309707 + 483 WP_271658683.1 transcription elongation factor GreAB -
PI990_RS23965 (PI990_23965) 5309759..5310160 + 402 WP_271658684.1 hypothetical protein -
PI990_RS23970 (PI990_23970) 5310350..5310535 + 186 WP_081672335.1 hypothetical protein -
PI990_RS23975 (PI990_23975) 5310553..5310999 - 447 WP_265169509.1 S24 family peptidase -
PI990_RS23980 (PI990_23980) 5311102..5312700 - 1599 WP_271658685.1 M28 family metallopeptidase -
PI990_RS23985 (PI990_23985) 5313209..5313760 + 552 WP_271658686.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(58-206)

Antitoxin

Antitoxin Xre/MbcA/ParS-like, toxin-binding domain

(72-121)


Sequences

Toxin        


Download         Length: 251 a.a.        Molecular weight: 28271.26 Da        Isoelectric Point: 6.6435

>T268499 WP_271658682.1 NZ_CP116239:c5308693-5307941 [Pseudomonas sp. TUM22785]
MDIWTTCQGSERIRPLRGRLVRLVESQEQVATLQLVDNLAEQALLEELIETSKPPLPRSAEPLHYLLKTPFRYPPLRWGS
RFGTVHEPSLFYAASRLETAMAEGAFYRFVLWSGMAVPPPSGRILSEHSSFEARFQVERGVQLQLPPFDAHDEALADPVD
YRTSQALGAAMRAAGVEAFEYRSARCPLQGTNIALFTPEAFTERRPRNLTPWLCETTAEYVAFKHAQAPDTPRLFRMTQF
LVDGRLPQPA

Download         Length: 753 bp

Antitoxin


Download         Length: 124 a.a.        Molecular weight: 13584.81 Da        Isoelectric Point: 10.2920

>AT268499 WP_021221398.1 NZ_CP116239:c5309101-5308730 [Pseudomonas sp. TUM22785]
MSALSRPTLDPDAVLAKALLNTREQLGLTQQQLADIVGVHRTAITRWADSGGIRPQSKTGELALLLIRAYRALFALFGGN
LDDMRHFLRTENRHLGAVPLELMAQVQGLVRVVEYLDAIRGKI

Download         Length: 372 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References