Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | vapBC/- |
| Location | 2795788..2797037 | Replicon | chromosome |
| Accession | NZ_CP116239 | ||
| Organism | Pseudomonas sp. TUM22785 | ||
Toxin (Protein)
| Gene name | vapC | Uniprot ID | - |
| Locus tag | PI990_RS12910 | Protein ID | WP_271660845.1 |
| Coordinates | 2796459..2797037 (+) | Length | 193 a.a. |
Antitoxin (Protein)
| Gene name | vapB | Uniprot ID | - |
| Locus tag | PI990_RS12905 | Protein ID | WP_271660844.1 |
| Coordinates | 2795788..2796345 (+) | Length | 186 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PI990_RS12885 (PI990_12885) | 2791142..2791753 | + | 612 | WP_271660841.1 | LysE family translocator | - |
| PI990_RS12890 (PI990_12890) | 2791757..2793844 | - | 2088 | WP_271660842.1 | response regulator | - |
| PI990_RS12895 (PI990_12895) | 2794032..2794787 | + | 756 | WP_271660843.1 | NAD-dependent deacylase | - |
| PI990_RS12900 (PI990_12900) | 2794816..2795331 | - | 516 | WP_184491277.1 | thioredoxin family protein | - |
| PI990_RS12905 (PI990_12905) | 2795788..2796345 | + | 558 | WP_271660844.1 | helix-turn-helix transcriptional regulator | Antitoxin |
| PI990_RS12910 (PI990_12910) | 2796459..2797037 | + | 579 | WP_271660845.1 | HD domain-containing protein | Toxin |
| PI990_RS12915 (PI990_12915) | 2797224..2797607 | + | 384 | WP_271660846.1 | cytochrome c | - |
| PI990_RS12920 (PI990_12920) | 2797645..2797785 | - | 141 | WP_081672307.1 | DUF2256 domain-containing protein | - |
| PI990_RS12925 (PI990_12925) | 2797782..2799326 | - | 1545 | WP_271660847.1 | cryptochrome/photolyase family protein | - |
| PI990_RS12930 (PI990_12930) | 2799320..2799625 | - | 306 | WP_021220926.1 | DUF6482 family protein | - |
| PI990_RS12935 (PI990_12935) | 2799656..2800192 | - | 537 | WP_271660848.1 | DUF3833 domain-containing protein | - |
| PI990_RS12940 (PI990_12940) | 2800204..2800755 | - | 552 | WP_271660849.1 | chalcone isomerase family protein | - |
| PI990_RS12945 (PI990_12945) | 2801075..2801383 | - | 309 | WP_271660850.1 | DUF4387 domain-containing protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 193 a.a. Molecular weight: 21386.00 Da Isoelectric Point: 4.6071
>T268496 WP_271660845.1 NZ_CP116239:2796459-2797037 [Pseudomonas sp. TUM22785]
MNIDRIKGRLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AIEQGGHPDKGAQEREDLLTLTRTLDAALRDEILALWDDYENAASPEALAVKALDKLETLLQHNQGANPADFDYAFNLGY
GRRYTSDEPLFAAIREQLDAGTRQRMEAQAGE
MNIDRIKGRLDFLREAERLKDVLRSAHTSSGRAESTAEHSWRLCLMAITFADELAGLDLLRVLKMCVVHDLGEAIHGDIP
AIEQGGHPDKGAQEREDLLTLTRTLDAALRDEILALWDDYENAASPEALAVKALDKLETLLQHNQGANPADFDYAFNLGY
GRRYTSDEPLFAAIREQLDAGTRQRMEAQAGE
Download Length: 579 bp
Antitoxin
Download Length: 186 a.a. Molecular weight: 20347.57 Da Isoelectric Point: 8.7936
>AT268496 WP_271660844.1 NZ_CP116239:2795788-2796345 [Pseudomonas sp. TUM22785]
MNDSLLKPAVLGVALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGVQEMEPAERARVEQMLAARLEAAADQALARLVSD
SPRAVHLVCDLSHRLLACSAARAAEFSIPLAELMGRSLWRYATPEIARKEAALDALGWRDLLMPPALEFGSGTNDSAIVP
IRQGLCRWTRMTLSDGTAARLVETL
MNDSLLKPAVLGVALRRWRLLHRVKQAHAAQLFGVAQSTISRWESGVQEMEPAERARVEQMLAARLEAAADQALARLVSD
SPRAVHLVCDLSHRLLACSAARAAEFSIPLAELMGRSLWRYATPEIARKEAALDALGWRDLLMPPALEFGSGTNDSAIVP
IRQGLCRWTRMTLSDGTAARLVETL
Download Length: 558 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|