Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1682647..1684342 Replicon chromosome
Accession NZ_CP116239
Organism Pseudomonas sp. TUM22785

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag PI990_RS07935 Protein ID WP_271660303.1
Coordinates 1682647..1683522 (+) Length 292 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag PI990_RS07940 Protein ID WP_271660304.1
Coordinates 1683509..1684342 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PI990_RS07910 (PI990_07910) 1678664..1679515 + 852 WP_271660298.1 ABC transporter ATP-binding protein -
PI990_RS07915 (PI990_07915) 1679547..1680542 + 996 WP_271660299.1 ABC transporter substrate-binding protein -
PI990_RS07920 (PI990_07920) 1680552..1681328 + 777 WP_271660300.1 ABC transporter permease -
PI990_RS07925 (PI990_07925) 1681334..1682095 + 762 WP_271660301.1 SDR family oxidoreductase -
PI990_RS07930 (PI990_07930) 1682109..1682639 + 531 WP_271660302.1 cupin domain-containing protein -
PI990_RS07935 (PI990_07935) 1682647..1683522 + 876 WP_271660303.1 alpha/beta hydrolase Toxin
PI990_RS07940 (PI990_07940) 1683509..1684342 + 834 WP_271660304.1 IclR family transcriptional regulator Antitoxin
PI990_RS07945 (PI990_07945) 1684329..1685126 + 798 WP_271660305.1 SDR family oxidoreductase -
PI990_RS07950 (PI990_07950) 1685119..1686801 + 1683 WP_271660306.1 thiamine pyrophosphate-binding protein -
PI990_RS07955 (PI990_07955) 1686812..1687615 + 804 WP_271660307.1 aspartate dehydrogenase -
PI990_RS07960 (PI990_07960) 1687626..1689110 + 1485 WP_184491507.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(41-272)

Antitoxin

Transcription regulator IclR, C-terminal

(130-253)


Sequences

Toxin        


Download         Length: 292 a.a.        Molecular weight: 30883.55 Da        Isoelectric Point: 7.7614

>T268495 WP_271660303.1 NZ_CP116239:1682647-1683522 [Pseudomonas sp. TUM22785]
MDMAQPPIPTTRLQQCFPERLVTVAEGARVAIRECGQGPVVVLLHGIGSGAASWLHCAQRLAGDHRVIAWDAPGYGRSTP
LPEARPRALDYATRLDGLLAALDIQRCLLVGHSLGALMATAYAASSGARRVARLVLFSPARGYGAEPLREAGRRVRQQRL
DSLERLGIGGMACERSGRLLGRNPSEDAQAWVRWNMARLNPEGYRQAVELLCGDDLLGQGLPAMPCEVHCGEEDAITVPE
ACGVLARALGASFSLIPGAGHACPIEQPEVVAGRIGHAQRLIVEGAACGKA

Download         Length: 876 bp

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 31026.61 Da        Isoelectric Point: 7.1504

>AT268495 WP_271660304.1 NZ_CP116239:1683509-1684342 [Pseudomonas sp. TUM22785]
VEKPDDPHDRYIVPGLERGLRLLCEFSRKNRTLTAPELARRLKLPRSTLFRLLATLEAMGFVCRNGNEYRLGMAVLRLGF
EYLASLELTELGQPLLNRLCDEVRYPCNLVVRDGRSIVYVAKVSPSTLLTSTVNVGTRLPAHATVLGRILLQDLPFTELR
ELYPEERLERFSPNTPATVLELFDLVQADRLRGFVQGEGFFEATISTVAAPVRDHSGRVVAAVGATIPSGRIEPDLLDGL
VSSVRHHADELSRLLDYTPDGRDKVASHHWSKQHEPV

Download         Length: 834 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References