Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 795309..795871 Replicon chromosome
Accession NZ_CP116239
Organism Pseudomonas sp. TUM22785

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PI990_RS03725 Protein ID WP_271659853.1
Coordinates 795554..795871 (+) Length 106 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PI990_RS03720 Protein ID WP_271659852.1
Coordinates 795309..795554 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PI990_RS03700 (PI990_03700) 791452..792657 + 1206 WP_271659848.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
PI990_RS03705 (PI990_03705) 792702..793799 + 1098 WP_271659849.1 cobalt-precorrin-5B (C(1))-methyltransferase -
PI990_RS03710 (PI990_03710) 793796..794527 + 732 WP_271659850.1 cobalt-precorrin-6A reductase -
PI990_RS03715 (PI990_03715) 794524..795231 + 708 WP_271659851.1 (2Fe-2S) ferredoxin domain-containing protein -
PI990_RS03720 (PI990_03720) 795309..795554 + 246 WP_271659852.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
PI990_RS03725 (PI990_03725) 795554..795871 + 318 WP_271659853.1 CcdB family protein Toxin
PI990_RS03730 (PI990_03730) 795882..797024 - 1143 WP_271659854.1 MFS transporter -
PI990_RS03735 (PI990_03735) 797372..798004 - 633 WP_271659855.1 VWA domain-containing protein -
PI990_RS03740 (PI990_03740) 798025..799029 - 1005 WP_271659856.1 AAA family ATPase -
PI990_RS03745 (PI990_03745) 799552..800640 + 1089 WP_271659857.1 3-deoxy-7-phosphoheptulonate synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(3-104)

Antitoxin

Post-segregation antitoxin CcdA

(11-81)


Sequences

Toxin        


Download         Length: 106 a.a.        Molecular weight: 11339.26 Da        Isoelectric Point: 4.4685

>T268492 WP_271659853.1 NZ_CP116239:795554-795871 [Pseudomonas sp. TUM22785]
MPQFAVHLNTNPATRAKIPYLLDVQSDLIDGLATRLIVPLYIDDILDGRAVGTLMPKFEVEGTTVVMFTPELAGVPRNVL
GAQVADLSGHRFEIIAALDLLITGI

Download         Length: 318 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 9138.29 Da        Isoelectric Point: 6.4642

>AT268492 WP_271659852.1 NZ_CP116239:795309-795554 [Pseudomonas sp. TUM22785]
MPALYNAQAPKKAANLSINSDLLSKARSLDINLSSTLEQALVEALKTRQREVWLEENREAIAAYNQHVEEHGVFSDGLRR
F

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References