Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 583042..583612 Replicon chromosome
Accession NZ_CP116234
Organism Helicobacter pylori strain H390d

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PHA49_RS02795 Protein ID WP_271331028.1
Coordinates 583340..583612 (+) Length 91 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PHA49_RS02790 Protein ID WP_180669626.1
Coordinates 583042..583353 (+) Length 104 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA49_RS02760 (PHA49_02760) 578588..579214 - 627 WP_271331024.1 helicase DnaB modulator -
PHA49_RS02775 (PHA49_02775) 579625..581850 + 2226 WP_271331025.1 Hop family adhesin BabA -
PHA49_RS02780 (PHA49_02780) 582339..582716 + 378 WP_271331026.1 hypothetical protein -
PHA49_RS02785 (PHA49_02785) 582697..582963 + 267 WP_271331027.1 type II toxin-antitoxin system YafQ family toxin -
PHA49_RS02790 (PHA49_02790) 583042..583353 + 312 WP_180669626.1 type II toxin-antitoxin system antitoxin Antitoxin
PHA49_RS02795 (PHA49_02795) 583340..583612 + 273 WP_271331028.1 type II toxin-antitoxin system YafQ family toxin Toxin
PHA49_RS02800 (PHA49_02800) 583718..584242 - 525 WP_001120212.1 acyl-CoA thioesterase -
PHA49_RS02805 (PHA49_02805) 584385..585227 + 843 WP_271331029.1 SDR family oxidoreductase -
PHA49_RS02810 (PHA49_02810) 585220..586200 + 981 WP_000921438.1 iron ABC transporter permease -
PHA49_RS02815 (PHA49_02815) 586200..586967 + 768 WP_024422093.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-90)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 91 a.a.        Molecular weight: 10641.69 Da        Isoelectric Point: 9.7265

>T268489 WP_271331028.1 NZ_CP116234:583340-583612 [Helicobacter pylori]
MLMIEISKKFDKDLKILVKNGFDLKLLYKVVENLTKEQPLDPKYKDHPLKGALKDFRECHLKPDLLLVYQIKKQENTLFL
VRLGSHSELF

Download         Length: 273 bp

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 12301.14 Da        Isoelectric Point: 10.1678

>AT268489 WP_180669626.1 NZ_CP116234:583042-583353 [Helicobacter pylori]
MPNSPAKKDYTQYSEKQLFNFLNSIKTKQKRALEKLKEIQAQKQRIKKALQFKALHLTENGYTIEEEREILARAKDTKNH
LCFKNIEDFKKHCENLRFKNADD

Download         Length: 312 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References