Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | yoeB-Axe/YoeB-RelB |
| Location | 1982540..1983047 | Replicon | chromosome |
| Accession | NZ_CP116231 | ||
| Organism | Fusobacterium nucleatum strain JD-Fn1 | ||
Toxin (Protein)
| Gene name | yoeB | Uniprot ID | U7TRZ4 |
| Locus tag | PGW91_RS09135 | Protein ID | WP_023037539.1 |
| Coordinates | 1982787..1983047 (+) | Length | 87 a.a. |
Antitoxin (Protein)
| Gene name | Axe | Uniprot ID | U7TRN8 |
| Locus tag | PGW91_RS09130 | Protein ID | WP_005892688.1 |
| Coordinates | 1982540..1982794 (+) | Length | 85 a.a. |
Genomic Context
Location: 1979399..1979761 (363 bp)
Type: Others
Protein ID: WP_271333008.1
Type: Others
Protein ID: WP_271333008.1
Location: 1979763..1981046 (1284 bp)
Type: Others
Protein ID: WP_271333009.1
Type: Others
Protein ID: WP_271333009.1
Location: 1981039..1982247 (1209 bp)
Type: Others
Protein ID: WP_271333010.1
Type: Others
Protein ID: WP_271333010.1
Location: 1982540..1982794 (255 bp)
Type: Antitoxin
Protein ID: WP_005892688.1
Type: Antitoxin
Protein ID: WP_005892688.1
Location: 1982787..1983047 (261 bp)
Type: Toxin
Protein ID: WP_023037539.1
Type: Toxin
Protein ID: WP_023037539.1
Location: 1983057..1983561 (505 bp)
Type: Others
Protein ID: Protein_1786
Type: Others
Protein ID: Protein_1786
Location: 1983589..1984077 (489 bp)
Type: Others
Protein ID: WP_271333823.1
Type: Others
Protein ID: WP_271333823.1
Location: 1984158..1984808 (651 bp)
Type: Others
Protein ID: WP_032848409.1
Type: Others
Protein ID: WP_032848409.1
Location: 1984887..1986083 (1197 bp)
Type: Others
Protein ID: WP_005895386.1
Type: Others
Protein ID: WP_005895386.1
Location: 1986146..1986532 (387 bp)
Type: Others
Protein ID: WP_005895388.1
Type: Others
Protein ID: WP_005895388.1
Location: 1986615..1987895 (1281 bp)
Type: Others
Protein ID: WP_271333012.1
Type: Others
Protein ID: WP_271333012.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PGW91_RS09115 (PGW91_09115) | 1979399..1979761 | + | 363 | WP_271333008.1 | Spx/MgsR family RNA polymerase-binding regulatory protein | - |
| PGW91_RS09120 (PGW91_09120) | 1979763..1981046 | + | 1284 | WP_271333009.1 | branched-chain amino acid transport system II carrier protein | - |
| PGW91_RS09125 (PGW91_09125) | 1981039..1982247 | + | 1209 | WP_271333010.1 | tyrosine--tRNA ligase | - |
| PGW91_RS09130 (PGW91_09130) | 1982540..1982794 | + | 255 | WP_005892688.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | Antitoxin |
| PGW91_RS09135 (PGW91_09135) | 1982787..1983047 | + | 261 | WP_023037539.1 | Txe/YoeB family addiction module toxin | Toxin |
| PGW91_RS09140 (PGW91_09140) | 1983057..1983561 | + | 505 | Protein_1786 | GNAT family N-acetyltransferase | - |
| PGW91_RS09145 (PGW91_09145) | 1983589..1984077 | + | 489 | WP_271333823.1 | GNAT family protein | - |
| PGW91_RS09150 (PGW91_09150) | 1984158..1984808 | + | 651 | WP_032848409.1 | endonuclease III | - |
| PGW91_RS09155 (PGW91_09155) | 1984887..1986083 | + | 1197 | WP_005895386.1 | cysteine desulfurase NifS | - |
| PGW91_RS09160 (PGW91_09160) | 1986146..1986532 | + | 387 | WP_005895388.1 | Fe-S cluster assembly scaffold protein NifU | - |
| PGW91_RS09165 (PGW91_09165) | 1986615..1987895 | + | 1281 | WP_271333012.1 | D-alanyl-D-alanine carboxypeptidase | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Structures
Toxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | U7TRZ4 |
Antitoxin
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Source | ID | Structure |
|---|---|---|
| AlphaFold DB | A0A806UAF3 |