Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 1527507..1528164 Replicon chromosome
Accession NZ_CP116222
Organism Providencia vermicola strain PVA41-chromosome

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PG365_RS06600 Protein ID WP_163860914.1
Coordinates 1527754..1528164 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag PG365_RS06595 Protein ID WP_154624313.1
Coordinates 1527507..1527773 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG365_RS06580 (PG365_06580) 1522659..1525535 + 2877 WP_251463864.1 aminomethyl-transferring glycine dehydrogenase -
PG365_RS06585 (PG365_06585) 1525632..1526252 - 621 WP_154624315.1 HD domain-containing protein -
PG365_RS06590 (PG365_06590) 1526264..1527253 - 990 WP_154624314.1 tRNA-modifying protein YgfZ -
PG365_RS06595 (PG365_06595) 1527507..1527773 + 267 WP_154624313.1 FAD assembly factor SdhE Antitoxin
PG365_RS06600 (PG365_06600) 1527754..1528164 + 411 WP_163860914.1 protein YgfX Toxin
PG365_RS06605 (PG365_06605) 1528209..1528727 - 519 WP_154624312.1 flavodoxin FldB -
PG365_RS06610 (PG365_06610) 1528812..1529735 + 924 WP_154624329.1 site-specific tyrosine recombinase XerD -
PG365_RS06615 (PG365_06615) 1529755..1530456 + 702 WP_154624311.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PG365_RS06620 (PG365_06620) 1530466..1532199 + 1734 WP_196713356.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 15375.24 Da        Isoelectric Point: 10.8779

>T268469 WP_163860914.1 NZ_CP116222:1527754-1528164 [Providencia vermicola]
VVLWKSNLSISWKTQLFSTCAHGLVGFILLVAPWAPGNSMVWLPLLAIVIASWAKSQKSISKIKGTAVLVNGNKVQWKKN
EWNIIKQPWCSRVGILLTLSALQGKQQKIRLWIAKDALSEESWRNLNQLLLQYPDI

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10578.07 Da        Isoelectric Point: 4.7132

>AT268469 WP_154624313.1 NZ_CP116222:1527507-1527773 [Providencia vermicola]
MDIENKARIHWACRRGMRELDISIMPFFEYEYDSLSDKDKQTFVRLLECADPDLFNWLMNHGRPDDEELFGMVKLIQERN
KNRGPVEI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References