Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2162957..2163125 Replicon chromosome
Accession NZ_CP116214
Organism Klebsiella michiganensis strain 2563

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2163015..2163118 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2162957..2163125 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PHA56_RS10280 (PHA56_10285) 2158084..2160144 + 2061 WP_014229840.1 oligopeptidase B -
PHA56_RS10285 (PHA56_10290) 2160151..2160810 - 660 WP_014229839.1 exodeoxyribonuclease X -
PHA56_RS10290 (PHA56_10295) 2160889..2161119 - 231 WP_004103351.1 DNA polymerase III subunit theta -
PHA56_RS10295 (PHA56_10300) 2161255..2161629 + 375 WP_014229838.1 CopC domain-containing protein YobA -
PHA56_RS10300 (PHA56_10305) 2161634..2162503 + 870 WP_038424672.1 copper homeostasis membrane protein CopD -
PHA56_RS10305 (PHA56_10310) 2162520..2162858 + 339 WP_004103344.1 YebY family protein -
- 2162957..2163125 - 169 - - Antitoxin
- 2163015..2163118 + 104 - - Toxin
PHA56_RS10310 (PHA56_10315) 2163243..2164202 - 960 WP_025106131.1 spore coat protein U domain-containing protein -
PHA56_RS10315 (PHA56_10320) 2164217..2166547 - 2331 WP_076752314.1 fimbria/pilus outer membrane usher protein -
PHA56_RS10320 (PHA56_10325) 2166550..2167314 - 765 WP_042945473.1 fimbria/pilus periplasmic chaperone -
PHA56_RS10325 (PHA56_10330) 2167333..2167851 - 519 WP_004852079.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T268454 NZ_CP116214:2163015-2163118 [Klebsiella michiganensis]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 169 bp

>AT268454 NZ_CP116214:c2163125-2162957 [Klebsiella michiganensis]
AACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGTCCGCGACAAAAGTG
GACGAATAA

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References