Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | chpSB/PRK09812-ChpS |
Location | 4283913..4284508 | Replicon | chromosome |
Accession | NZ_CP116197 | ||
Organism | Escherichia coli strain DETEC-C31 |
Toxin (Protein)
Gene name | chpB | Uniprot ID | U9Y4M4 |
Locus tag | PIB97_RS20425 | Protein ID | WP_000239579.1 |
Coordinates | 4283913..4284263 (-) | Length | 117 a.a. |
Antitoxin (Protein)
Gene name | chpS | Uniprot ID | U9Y2K1 |
Locus tag | PIB97_RS20430 | Protein ID | WP_001223208.1 |
Coordinates | 4284257..4284508 (-) | Length | 84 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PIB97_RS20405 (4279359) | 4279359..4280381 | - | 1023 | WP_001313531.1 | ABC transporter permease | - |
PIB97_RS20410 (4280395) | 4280395..4281897 | - | 1503 | WP_021557471.1 | sugar ABC transporter ATP-binding protein | - |
PIB97_RS20415 (4282037) | 4282037..4282993 | - | 957 | WP_000265933.1 | galactofuranose ABC transporter substrate-binding protein YtfQ | - |
PIB97_RS20420 (4283303) | 4283303..4283833 | + | 531 | WP_000055072.1 | inorganic diphosphatase | - |
PIB97_RS20425 (4283913) | 4283913..4284263 | - | 351 | WP_000239579.1 | endoribonuclease toxin ChpB | Toxin |
PIB97_RS20430 (4284257) | 4284257..4284508 | - | 252 | WP_001223208.1 | type II toxin-antitoxin system antitoxin ChpS | Antitoxin |
PIB97_RS20435 (4284721) | 4284721..4285062 | - | 342 | WP_001219160.1 | gamma-glutamylcyclotransferase | - |
PIB97_RS20440 (4285065) | 4285065..4288844 | - | 3780 | WP_021557470.1 | autotransporter assembly complex protein TamB | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12511.45 Da Isoelectric Point: 5.6219
>T268429 WP_000239579.1 NZ_CP116197:c4284263-4283913 [Escherichia coli]
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE
MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLGMTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLV
NQVRMMDLRARLAKRIGLAADEVVEEALLRLQAVVE
Download Length: 351 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0E0Y8A8 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9LQ26 |