Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | ccdAB/CcdA(antitoxin) |
Location | 4029061..4029611 | Replicon | chromosome |
Accession | NZ_CP116197 | ||
Organism | Escherichia coli strain DETEC-C31 |
Toxin (Protein)
Gene name | ccdB | Uniprot ID | D3H432 |
Locus tag | PIB97_RS19210 | Protein ID | WP_001160975.1 |
Coordinates | 4029061..4029375 (-) | Length | 105 a.a. |
Antitoxin (Protein)
Gene name | ccdA | Uniprot ID | D3H431 |
Locus tag | PIB97_RS19215 | Protein ID | WP_000125565.1 |
Coordinates | 4029378..4029611 (-) | Length | 78 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PIB97_RS19185 (4024736) | 4024736..4026022 | + | 1287 | WP_000800457.1 | peptidylprolyl isomerase SurA | - |
PIB97_RS19190 (4026022) | 4026022..4027011 | + | 990 | WP_021556398.1 | 4-hydroxythreonine-4-phosphate dehydrogenase PdxA | - |
PIB97_RS19195 (4027008) | 4027008..4027829 | + | 822 | WP_001065381.1 | 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA | - |
PIB97_RS19200 (4027832) | 4027832..4028209 | + | 378 | WP_000610901.1 | Co2+/Mg2+ efflux protein ApaG | - |
PIB97_RS19205 (4028216) | 4028216..4029064 | + | 849 | WP_021556397.1 | bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH | - |
PIB97_RS19210 (4029061) | 4029061..4029375 | - | 315 | WP_001160975.1 | CcdB family protein | Toxin |
PIB97_RS19215 (4029378) | 4029378..4029611 | - | 234 | WP_000125565.1 | type II toxin-antitoxin system CcdA family antitoxin | Antitoxin |
PIB97_RS19220 (4029697) | 4029697..4030176 | - | 480 | WP_001487721.1 | type 3 dihydrofolate reductase | - |
PIB97_RS19225 (4030368) | 4030368..4032230 | - | 1863 | WP_040234481.1 | glutathione-regulated potassium-efflux system protein KefC | - |
PIB97_RS19230 (4032223) | 4032223..4032753 | - | 531 | WP_000600718.1 | glutathione-regulated potassium-efflux system oxidoreductase KefF | - |
PIB97_RS19235 (4032864) | 4032864..4034195 | - | 1332 | WP_001183198.1 | MFS transporter | - |
PIB97_RS19240 (4034253) | 4034253..4034540 | - | 288 | WP_000203741.1 | ferredoxin-like protein FixX | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11711.76 Da Isoelectric Point: 9.8517
>T268427 WP_001160975.1 NZ_CP116197:c4029375-4029061 [Escherichia coli]
MQFTVYRSRSRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRIRPPERLNPILLLVDGKEYVLMTHETATVPVNALG
TKFCDASAHRTLIKGALDFMLDGI
MQFTVYRSRSRNAAFPFVIDVTSDIIGVINRRIVIPLTPIERFSRIRPPERLNPILLLVDGKEYVLMTHETATVPVNALG
TKFCDASAHRTLIKGALDFMLDGI
Download Length: 315 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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