Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | hicAB/- |
Location | 286455..287086 | Replicon | chromosome |
Accession | NZ_CP116197 | ||
Organism | Escherichia coli strain DETEC-C31 |
Toxin (Protein)
Gene name | hicA | Uniprot ID | A0A1M1UJK7 |
Locus tag | PIB97_RS01255 | Protein ID | WP_001259382.1 |
Coordinates | 286455..286730 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | hicB | Uniprot ID | U9Y7E1 |
Locus tag | PIB97_RS01260 | Protein ID | WP_000593555.1 |
Coordinates | 286727..287086 (+) | Length | 120 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PIB97_RS01240 (281459) | 281459..282526 | + | 1068 | WP_000361517.1 | HlyD family efflux transporter periplasmic adaptor subunit | - |
PIB97_RS01245 (282523) | 282523..285258 | + | 2736 | WP_000149130.1 | ribosome-associated ATPase/putative transporter RbbA | - |
PIB97_RS01250 (285258) | 285258..286382 | + | 1125 | WP_021557290.1 | ABC transporter permease | - |
PIB97_RS01255 (286455) | 286455..286730 | + | 276 | WP_001259382.1 | type II toxin-antitoxin system HicA family toxin | Toxin |
PIB97_RS01260 (286727) | 286727..287086 | + | 360 | WP_000593555.1 | type II toxin-antitoxin system HicB family antitoxin | Antitoxin |
PIB97_RS01265 (287136) | 287136..287996 | - | 861 | WP_021557289.1 | class II aldolase | - |
PIB97_RS01270 (288028) | 288028..288297 | - | 270 | WP_000933060.1 | HPr family phosphocarrier protein | - |
PIB97_RS01275 (288287) | 288287..289795 | - | 1509 | WP_021557288.1 | FGGY-family carbohydrate kinase | - |
PIB97_RS01280 (289788) | 289788..291146 | - | 1359 | WP_001308116.1 | PTS galactitol transporter subunit IIC | - |
PIB97_RS01285 (291223) | 291223..291504 | - | 282 | WP_000084025.1 | PTS sugar transporter subunit IIB | - |
PIB97_RS01290 (291501) | 291501..291974 | - | 474 | WP_001161650.1 | PTS sugar transporter subunit IIA | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1M1UJK7 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U9LKZ6 |