Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 527108..527376 Replicon chromosome
Accession NZ_CP116145
Organism Escherichia coli strain DETEC-P622

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 527146..527248 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 527108..527376 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB88_RS02665 524266..525705 + 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
PIB88_RS02670 525822..526058 + 237 WP_001295499.1 YebV family protein -
PIB88_RS02675 526163..526354 + 192 WP_001296140.1 YebW family protein -
PIB88_RS02680 526355..527011 - 657 WP_000812745.1 protein-serine/threonine phosphatase -
- 527108..527376 + 269 - - Antitoxin
- 527146..527248 - 103 - - Toxin
PIB88_RS02685 527406..527747 - 342 WP_000976472.1 YebY family protein -
PIB88_RS02690 527760..528632 - 873 WP_000879317.1 copper homeostasis membrane protein CopD -
PIB88_RS02695 528636..529010 - 375 WP_000168747.1 CopC domain-containing protein YobA -
PIB88_RS02700 529149..529379 + 231 WP_000916763.1 DNA polymerase III subunit theta -
PIB88_RS02705 529481..530137 + 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
PIB88_RS02710 530161..530823 + 663 WP_000944256.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T268147 NZ_CP116145:c527248-527146 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT268147 NZ_CP116145:527108-527376 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References