Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202671..2202942 Replicon chromosome
Accession NZ_CP116136
Organism Escherichia coli strain DETEC-P649

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202801..2202904 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202671..2202942 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB66_RS10460 2199226..2199888 - 663 WP_000944256.1 exodeoxyribonuclease X -
PIB66_RS10465 2199912..2200568 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
PIB66_RS10470 2200670..2200900 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PIB66_RS10475 2201039..2201413 + 375 WP_000168747.1 CopC domain-containing protein YobA -
PIB66_RS10480 2201417..2202289 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
PIB66_RS10485 2202302..2202643 + 342 WP_000976472.1 YebY family protein -
- 2202671..2202942 - 272 - - Antitoxin
- 2202801..2202904 + 104 - - Toxin
PIB66_RS10490 2203039..2203695 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
PIB66_RS10495 2203696..2203887 - 192 WP_001296140.1 YebW family protein -
PIB66_RS10500 2203992..2204228 - 237 WP_001295499.1 YebV family protein -
PIB66_RS10505 2204346..2205785 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2195361..2205791 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T268125 NZ_CP116136:2202801-2202904 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT268125 NZ_CP116136:c2202942-2202671 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References