Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2202673..2202944 Replicon chromosome
Accession NZ_CP116123
Organism Escherichia coli strain DETEC-P666

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2202803..2202906 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2202673..2202944 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB57_RS10465 2199228..2199890 - 663 WP_000944256.1 exodeoxyribonuclease X -
PIB57_RS10470 2199914..2200570 - 657 WP_000011653.1 carbon-nitrogen hydrolase family protein YobB -
PIB57_RS10475 2200672..2200902 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PIB57_RS10480 2201041..2201415 + 375 WP_000168747.1 CopC domain-containing protein YobA -
PIB57_RS10485 2201419..2202291 + 873 WP_001551232.1 copper homeostasis membrane protein CopD -
PIB57_RS10490 2202304..2202645 + 342 WP_000976472.1 YebY family protein -
- 2202673..2202944 - 272 - - Antitoxin
- 2202803..2202906 + 104 - - Toxin
PIB57_RS10495 2203041..2203697 + 657 WP_001551231.1 protein-serine/threonine phosphatase -
PIB57_RS10500 2203698..2203889 - 192 WP_001296140.1 YebW family protein -
PIB57_RS10505 2203994..2204230 - 237 WP_001295499.1 YebV family protein -
PIB57_RS10510 2204348..2205787 - 1440 WP_024186439.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2195363..2205793 10430


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T268092 NZ_CP116123:2202803-2202906 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT268092 NZ_CP116123:c2202944-2202673 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGCCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References