Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YoeB-DinJ
Location 480839..481379 Replicon chromosome
Accession NC_017448
Organism Fibrobacter succinogenes subsp. succinogenes S85

Toxin (Protein)


Gene name relE Uniprot ID C9RJ03
Locus tag FSU_RS02030 Protein ID WP_012819877.1
Coordinates 481113..481379 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C9RJ02
Locus tag FSU_RS02025 Protein ID WP_012819876.1
Coordinates 480839..481120 (+) Length 94 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
FSU_RS02005 476556..477209 - 654 WP_012819872.1 hypothetical protein -
FSU_RS02010 477202..477951 - 750 WP_012819873.1 HD domain-containing protein -
FSU_RS02015 478020..479300 - 1281 WP_012819874.1 DUF285 domain-containing protein -
FSU_RS02020 479409..480725 + 1317 WP_012819875.1 hypothetical protein -
FSU_RS02025 480839..481120 + 282 WP_012819876.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
FSU_RS02030 481113..481379 + 267 WP_012819877.1 Txe/YoeB family addiction module toxin Toxin
FSU_RS02035 481437..482066 - 630 WP_012819878.1 hypothetical protein -
FSU_RS02040 482360..482578 - 219 WP_012819879.1 hypothetical protein -
FSU_RS02045 482611..482958 + 348 WP_012819880.1 hypothetical protein -
FSU_RS02050 482976..485570 + 2595 WP_014545224.1 U32 family peptidase -
FSU_RS02055 485573..485917 - 345 WP_012819882.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(3-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-88)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10445.91 Da        Isoelectric Point: 8.8944

>T26785 WP_012819877.1 NC_017448:481113-481379 [Fibrobacter succinogenes subsp. succinogenes S85]
MAKIAFSEQAWQEYLYWQLQDKKTLKRVNQLLKDIERNHFEGLGKPEALKGNLSGFWSRRIDDGNRLIYRINGEFIDILS
CKGHYENV

Download         Length: 267 bp

>T26785 NC_017448:481113-481379 [Fibrobacter succinogenes subsp. succinogenes S85]
ATGGCTAAAATCGCATTTTCCGAACAAGCGTGGCAAGAATATCTCTACTGGCAACTACAAGATAAGAAAACACTCAAAAG
AGTCAACCAACTGCTTAAAGACATCGAGCGAAACCATTTCGAAGGCTTAGGCAAGCCTGAAGCATTGAAAGGAAACCTCA
GCGGATTTTGGAGTCGACGAATTGACGATGGCAATCGGCTAATCTACAGAATTAATGGTGAATTTATCGACATTCTTTCT
TGCAAAGGTCACTACGAAAACGTTTAG

Antitoxin


Download         Length: 94 a.a.        Molecular weight: 10309.74 Da        Isoelectric Point: 5.1879

>AT26785 WP_012819876.1 NC_017448:480839-481120 [Fibrobacter succinogenes subsp. succinogenes S85]
MAQATVSARIDSKDKERFDEFCNNVGLSASAAINMFIKSVINEHRIPFEVREPIARYNAKANDIEALKKGIEQLNAGKGI
VKTLEELEAMENG

Download         Length: 282 bp

>AT26785 NC_017448:480839-481120 [Fibrobacter succinogenes subsp. succinogenes S85]
ATGGCACAGGCAACAGTTTCTGCACGAATCGACAGCAAAGACAAAGAACGTTTTGACGAATTCTGCAATAACGTTGGTTT
GTCCGCATCCGCAGCCATCAACATGTTCATCAAGAGCGTCATCAATGAACATCGCATTCCCTTTGAAGTCCGCGAACCCA
TAGCCCGTTACAACGCAAAAGCAAATGACATCGAGGCCCTCAAAAAAGGCATCGAACAGCTCAATGCCGGGAAAGGTATT
GTGAAAACACTAGAAGAACTAGAGGCAATGGAAAATGGCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A254SMJ7

Antitoxin

Source ID Structure
AlphaFold DB C9RJ02

References