Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2144588..2144859 Replicon chromosome
Accession NZ_CP116074
Organism Escherichia coli strain DETEC-S586

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2144718..2144821 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2144588..2144859 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIC49_RS10160 2141143..2141805 - 663 WP_000944256.1 exodeoxyribonuclease X -
PIC49_RS10165 2141829..2142485 - 657 WP_000011651.1 carbon-nitrogen hydrolase family protein YobB -
PIC49_RS10170 2142587..2142817 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PIC49_RS10175 2142956..2143330 + 375 WP_000204705.1 CopC domain-containing protein YobA -
PIC49_RS10180 2143334..2144206 + 873 WP_000879330.1 copper homeostasis membrane protein CopD -
PIC49_RS10185 2144219..2144560 + 342 WP_000976481.1 YebY family protein -
- 2144588..2144859 - 272 - - Antitoxin
- 2144718..2144821 + 104 - - Toxin
PIC49_RS10190 2144956..2145612 + 657 WP_001546849.1 protein-serine/threonine phosphatase -
PIC49_RS10195 2145613..2145804 - 192 WP_001296140.1 YebW family protein -
PIC49_RS10200 2145909..2146145 - 237 WP_001295499.1 YebV family protein -
PIC49_RS10205 2146263..2147702 - 1440 WP_001309555.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2137278..2161409 24131


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T267817 NZ_CP116074:2144718-2144821 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT267817 NZ_CP116074:c2144859-2144588 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGCGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References