Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 2150132..2150771 Replicon chromosome
Accession NZ_CP116040
Organism Acinetobacter haemolyticus strain HW-2

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PGW89_RS10125 Protein ID WP_113996648.1
Coordinates 2150376..2150771 (+) Length 132 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID N9FB90
Locus tag PGW89_RS10120 Protein ID WP_004641025.1
Coordinates 2150132..2150389 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGW89_RS10095 (PGW89_10095) 2145207..2145572 + 366 WP_004641032.1 50S ribosomal protein L17 -
PGW89_RS10100 (PGW89_10100) 2145737..2146234 + 498 WP_017395331.1 GNAT family N-acetyltransferase -
PGW89_RS10105 (PGW89_10105) 2146612..2148102 + 1491 WP_017395332.1 NAD(P)/FAD-dependent oxidoreductase -
PGW89_RS10110 (PGW89_10110) 2148225..2148722 + 498 WP_113996647.1 DUF2059 domain-containing protein -
PGW89_RS10115 (PGW89_10115) 2148773..2149945 - 1173 WP_005086825.1 acyl-CoA dehydrogenase family protein -
PGW89_RS10120 (PGW89_10120) 2150132..2150389 + 258 WP_004641025.1 succinate dehydrogenase assembly factor 2 Antitoxin
PGW89_RS10125 (PGW89_10125) 2150376..2150771 + 396 WP_113996648.1 hypothetical protein Toxin
PGW89_RS10130 (PGW89_10130) 2150982..2151188 + 207 WP_026056364.1 hypothetical protein -
PGW89_RS10135 (PGW89_10135) 2151548..2152591 + 1044 WP_113996649.1 hypothetical protein -
PGW89_RS10140 (PGW89_10140) 2152719..2153300 + 582 WP_004641018.1 rhombosortase -
PGW89_RS10145 (PGW89_10145) 2153478..2155688 + 2211 WP_004641016.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1998820..2161476 162656


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 16053.36 Da        Isoelectric Point: 9.1821

>T267674 WP_113996648.1 NZ_CP116040:2150376-2150771 [Acinetobacter haemolyticus]
MSTADRVFVLKRSRFAFAFQLFIFIVLISLLYYLLPWFLWLVSFPLMLIAWVLLLKQPQLKHFEYLDDQLCSLCFSDEMQ
GIEQRKIRKMIDHQCYIVIYFYDSQCRPCVIWWDQLSILQWKKLKKWVKLA

Download         Length: 396 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9982.42 Da        Isoelectric Point: 4.4558

>AT267674 WP_004641025.1 NZ_CP116040:2150132-2150389 [Acinetobacter haemolyticus]
MSEELTLEERKVIYRARRGLKEIDVYFDPYVKNCYLTADAAEKALFAELVDQEDPDLLDWFMEVGEPPRPELKAFISKLK
QYVHG

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB N9FB90

References