Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2148489..2148757 Replicon chromosome
Accession NZ_CP116035
Organism Escherichia coli strain FAH

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2148617..2148719 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2148489..2148757 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PGH49_RS10305 2145042..2145704 - 663 WP_000944258.1 exodeoxyribonuclease X -
PGH49_RS10310 2145728..2146384 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein YobB -
PGH49_RS10315 2146486..2146716 - 231 WP_000916763.1 DNA polymerase III subunit theta -
PGH49_RS10320 2146855..2147229 + 375 WP_000168747.1 CopC domain-containing protein YobA -
PGH49_RS10325 2147233..2148105 + 873 WP_000879311.1 copper homeostasis membrane protein CopD -
PGH49_RS10330 2148118..2148459 + 342 WP_000984819.1 YebY family protein -
- 2148489..2148757 - 269 - - Antitoxin
- 2148617..2148719 + 103 - - Toxin
PGH49_RS10335 2148854..2149510 + 657 WP_000812744.1 protein-serine/threonine phosphatase -
PGH49_RS10340 2149511..2149702 - 192 WP_024186842.1 YebW family protein -
PGH49_RS10345 2149807..2150043 - 237 WP_001295499.1 YebV family protein -
PGH49_RS10350 2150162..2151601 - 1440 WP_024186841.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T267647 NZ_CP116035:2148617-2148719 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT267647 NZ_CP116035:c2148757-2148489 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References