Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/PRK09907(toxin)
Location 1001201..1001772 Replicon chromosome
Accession NZ_CP116026
Organism Enterococcus casseliflavus strain CQFYY22-063

Toxin (Protein)


Gene name mazF Uniprot ID -
Locus tag PEZ80_RS04735 Protein ID WP_087627127.1
Coordinates 1001201..1001542 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name mazE Uniprot ID -
Locus tag PEZ80_RS04740 Protein ID WP_142973751.1
Coordinates 1001542..1001772 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PEZ80_RS04710 (PEZ80_04710) 996229..997095 + 867 WP_271292493.1 class II fructose-bisphosphate aldolase family protein -
PEZ80_RS04715 (PEZ80_04715) 997096..997722 + 627 WP_142973750.1 zeta toxin family protein -
PEZ80_RS04720 (PEZ80_04720) 997766..998770 - 1005 WP_271292494.1 DUF389 domain-containing protein -
PEZ80_RS04725 (PEZ80_04725) 998960..999559 + 600 WP_074932236.1 NUDIX hydrolase -
PEZ80_RS04730 (PEZ80_04730) 999720..1001030 + 1311 WP_271292495.1 NCS2 family permease -
PEZ80_RS04735 (PEZ80_04735) 1001201..1001542 - 342 WP_087627127.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
PEZ80_RS04740 (PEZ80_04740) 1001542..1001772 - 231 WP_142973751.1 AbrB family transcriptional regulator Antitoxin
PEZ80_RS04745 (PEZ80_04745) 1002138..1003133 + 996 WP_010747735.1 LacI family DNA-binding transcriptional regulator -
PEZ80_RS04750 (PEZ80_04750) 1003280..1004656 + 1377 WP_096741465.1 PTS transporter subunit EIIC -
PEZ80_RS04755 (PEZ80_04755) 1004700..1006142 + 1443 WP_271292496.1 glycoside hydrolase family 32 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(7-112)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13302.53 Da        Isoelectric Point: 9.4138

>T267639 WP_087627127.1 NZ_CP116026:c1001542-1001201 [Enterococcus casseliflavus]
MMNDQTYIPKKGDIVWIDFDPSAGKEIQKRRPGLVVSRYEFNRRTMFAVICPITHTIRKFPTHYTLPDSIDTDGQVIISQ
LKSLDFKERKLKKIENLPLQDMAKIDQIIEYIF

Download         Length: 342 bp

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 8643.58 Da        Isoelectric Point: 3.9191

>AT267639 WP_142973751.1 NZ_CP116026:c1001772-1001542 [Enterococcus casseliflavus]
MLITKSRLQGSSVVITLPSDNGKKPSENQEYVVVYAEDGTIILVPKIEDPFYGGEESEFYEKDEWEDLSPEGREIF

Download         Length: 231 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References