267637

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 457152..457681 Replicon chromosome
Accession NZ_CP116026
Organism Enterococcus casseliflavus strain CQFYY22-063

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PEZ80_RS02180 Protein ID WP_081116192.1
Coordinates 457415..457681 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A377KQM1
Locus tag PEZ80_RS02175 Protein ID WP_010748737.1
Coordinates 457152..457415 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PEZ80_RS02160 (PEZ80_02160) 452721..453986 - 1266 WP_208773556.1 glycoside hydrolase family 27 protein -
PEZ80_RS02165 (PEZ80_02165) 454107..455006 + 900 WP_081116191.1 AraC family transcriptional regulator -
PEZ80_RS02170 (PEZ80_02170) 455057..456997 + 1941 WP_010748736.1 glycoside hydrolase family 127 protein -
PEZ80_RS02175 (PEZ80_02175) 457152..457415 + 264 WP_010748737.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PEZ80_RS02180 (PEZ80_02180) 457415..457681 + 267 WP_081116192.1 Txe/YoeB family addiction module toxin Toxin
PEZ80_RS02185 (PEZ80_02185) 457874..460705 + 2832 WP_081116193.1 discoidin domain-containing protein -
PEZ80_RS02190 (PEZ80_02190) 460837..461499 - 663 WP_005227316.1 ABC transporter permease -
PEZ80_RS02195 (PEZ80_02195) 461504..462424 - 921 WP_010748740.1 osmoprotectant ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10672.16 Da        Isoelectric Point: 10.0683

>T267637 WP_081116192.1 NZ_CP116026:457415-457681 [Enterococcus casseliflavus]
MRSDTVTIKNSAKVDLRKIKQSNLKKQFEEVIQALKEDPYMPTQSFEKLRPTHEGRYSRRLNRQHRMVYKVDEENKVVEI
YSAWTHYE

Download         Length: 267 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9958.03 Da        Isoelectric Point: 4.2682

>AT267637 WP_010748737.1 NZ_CP116026:457152-457415 [Enterococcus casseliflavus]
MAKTTMNPSTARKNFYQLLKDVNENHTEIEIISDRSGNNAVLIGLGDWRAIQETLFLEQTGTLEKVRDREKDDSGFTDID
DIDWQAL

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A377KQM1

References