267628

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) spoIISABC/SpoIISA-SpoIISB
Location 2959268..2960184 Replicon chromosome
Accession NZ_CP116012
Organism Bacillus subtilis strain SRCM124333

Toxin (Protein)


Gene name spoIISA Uniprot ID -
Locus tag PF977_RS15520 Protein ID WP_015715744.1
Coordinates 2959268..2960014 (+) Length 249 a.a.

Antitoxin (Protein)


Gene name spoIISB Uniprot ID -
Locus tag PF977_RS15525 Protein ID WP_015715743.1
Coordinates 2960014..2960184 (+) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PF977_RS15495 (2954392) 2954392..2954487 - 96 Protein_3061 hypothetical protein -
PF977_RS15500 (2954596) 2954596..2955546 - 951 WP_015715745.1 ring-cleaving dioxygenase -
PF977_RS15505 (2955935) 2955935..2957251 + 1317 WP_015252262.1 serine/threonine exchanger -
PF977_RS15510 (2957527) 2957527..2958144 + 618 WP_003218470.1 DUF47 domain-containing protein -
PF977_RS15515 (2958157) 2958157..2959158 + 1002 WP_014479569.1 inorganic phosphate transporter -
PF977_RS15520 (2959268) 2959268..2960014 + 747 WP_015715744.1 toxin-antitoxin-antitoxin system toxin SpoIISA Toxin
PF977_RS15525 (2960014) 2960014..2960184 + 171 WP_015715743.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISB Antitoxin
PF977_RS15530 (2960270) 2960270..2960410 + 141 WP_144460135.1 three component toxin-antitoxin-antitoxin system antitoxin SpoIISC -
PF977_RS15535 (2960448) 2960448..2961341 - 894 WP_015715742.1 N-acetylmuramoyl-L-alanine amidase -
PF977_RS15540 (2961354) 2961354..2961617 - 264 WP_014479566.1 phage holin -
PF977_RS15545 (2961630) 2961630..2961899 - 270 WP_003232655.1 hemolysin XhlA family protein -
PF977_RS15550 (2961952) 2961952..2962791 - 840 WP_015715741.1 phage-like element PBSX protein XepA -
PF977_RS15555 (2962835) 2962835..2962999 - 165 WP_015715740.1 XkdX family protein -
PF977_RS15560 (2962996) 2962996..2963325 - 330 WP_003232660.1 XkdW family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin SpoIISA, type II toxin-antitoxin system

(3-238)

Antitoxin

Antitoxin SpoIISB

(1-56)


Sequences

Toxin        


Download         Length: 249 a.a.        Molecular weight: 29043.47 Da        Isoelectric Point: 4.6191

>T267628 WP_015715744.1 NZ_CP116012:2959268-2960014 [Bacillus subtilis]
MVLFFQIMVWCIVAGLGLYVYATWRFEAKVKEKMSAIRKTWYLLFVLGAMVYWTYEPTSLFTHWERYLIVAVSFALIDAF
IFLSAYVKKLAGSELETDTREILEENNEMLHIYLNRLKTYQYLLKNEPIHVYYGSIDAYAEGIDKLLKTYADKMNLTASL
CHYSTQADKDRLTEHMDDPADVQTRLDRKDVYYDQYGKVVLIPFTIETQNYVIKLTSDSIVTEFDYLLFTSLTSIYDLVL
PIEEEGEG

Download         Length: 747 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6682.74 Da        Isoelectric Point: 11.1467

>AT267628 WP_015715743.1 NZ_CP116012:2960014-2960184 [Bacillus subtilis]
MERAFQNRCEPRAAKPFKILKKRSTTSVASYQVSPHTARIFKENERLIDEYKRKRA

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References