Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 1369704..1371421 Replicon chromosome
Accession NZ_CP116007
Organism Pseudoxanthomonas mexicana strain DMF-5

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag PE064_RS06595 Protein ID WP_271251099.1
Coordinates 1370771..1371421 (-) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag PE064_RS06590 Protein ID WP_271251098.1
Coordinates 1369704..1370771 (-) Length 356 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PE064_RS06575 (PE064_06575) 1365014..1366720 + 1707 WP_271251095.1 membrane protein insertase YidC -
PE064_RS06580 (PE064_06580) 1366809..1368158 + 1350 WP_271251096.1 tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE -
PE064_RS06585 (PE064_06585) 1368341..1369546 + 1206 WP_271251097.1 tyrosine-type recombinase/integrase -
PE064_RS06590 (PE064_06590) 1369704..1370771 - 1068 WP_271251098.1 macro domain-containing protein Antitoxin
PE064_RS06595 (PE064_06595) 1370771..1371421 - 651 WP_271251099.1 DUF4433 domain-containing protein Toxin
PE064_RS06600 (PE064_06600) 1371414..1372658 - 1245 WP_271251100.1 SH3 domain-containing protein -
PE064_RS06605 (PE064_06605) 1372651..1375866 - 3216 WP_271251101.1 type I restriction endonuclease subunit R -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(16-216)

Antitoxin

Macro domain

(18-129)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 24881.28 Da        Isoelectric Point: 7.0234

>T267614 WP_271251099.1 NZ_CP116007:c1371421-1370771 [Pseudoxanthomonas mexicana]
MANHYPNLNPEKALIWRIVHRDNLSWILDNGLHCGNGGMQAPGWVSIGNPELIDKRASHPVPLPPGGFLNDYVPFYFTPF
SPMLRNIHTGWGGIQRRPNEEIVILVSSLHHVAAQGWPFLFTDSHAYYQWANFYSDLAGVDKIDWPLLQARDFRRDPEDP
AKFERYQAEALIHRHLPINGLLGVVCYTDNLRQVIEQQIQARNLNLPVYARTGWYF

Download         Length: 651 bp

Antitoxin


Download         Length: 356 a.a.        Molecular weight: 39897.85 Da        Isoelectric Point: 6.5093

>AT267614 WP_271251098.1 NZ_CP116007:c1370771-1369704 [Pseudoxanthomonas mexicana]
MITFTQGNLLEARAEALVNTVNTVGVMGKGIALMFKERFADNFRRYAVACKAKEVRTGKMFVTEVNELDGPRWIVNFPTK
QHWRGDSKIEWITDGLQDLRRFLIENKVKSIAIPPLGAGNGGLDWAEVRPQIEDALAGLDTEILVFEPTQKYQNVAKRTG
VEKLTPARALIAELVRRYWVLGMECSLLEIQKLAWFLERSIERTSLTPLDLRFVPHKYGPYADRLRHLLEGLDGSYLHCD
KRIGDADPLDVIWFDDGRKTFVQTYLKSEAKDYVPALEATAALIDGFESPYGMELLSTVDWLLSQEGVAPTVPAVREGLH
HWRGGPGAAARKDRLFDDRALSIALERLASSTVVA

Download         Length: 1068 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References