Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/HicA-HicA
Location 1065175..1065587 Replicon chromosome
Accession NZ_CP116007
Organism Pseudoxanthomonas mexicana strain DMF-5

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PE064_RS05185 Protein ID WP_271250895.1
Coordinates 1065393..1065587 (-) Length 65 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PE064_RS05180 Protein ID WP_271250894.1
Coordinates 1065175..1065387 (-) Length 71 a.a.

Genomic Context

PE064_RS05155PE064_RS05165PE064_RS05160PE064_RS05170PE064_RS05175PE064_RS05180PE064_RS05185PE064_RS05190
Location: 1061221..1061892 (672 bp)
Type: Others
Protein ID: WP_187574066.1
Location: 1062451..1063359 (909 bp)
Type: Others
Protein ID: WP_271250891.1
Location: 1061943..1062260 (318 bp)
Type: Others
Protein ID: WP_271250890.1
Location: 1063349..1063918 (570 bp)
Type: Others
Protein ID: WP_271250892.1
Location: 1064038..1065135 (1098 bp)
Type: Others
Protein ID: WP_271250893.1
Location: 1065175..1065387 (213 bp)
Type: Antitoxin
Protein ID: WP_271250894.1
Location: 1065393..1065587 (195 bp)
Type: Toxin
Protein ID: WP_271250895.1
Location: 1065678..1068371 (2694 bp)
Type: Others
Protein ID: WP_271250896.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
PE064_RS05155 (PE064_05155)1061221..1061892+672WP_187574066.1Fe2+-dependent dioxygenase-
PE064_RS05160 (PE064_05160)1061943..1062260-318WP_271250890.1DUF3817 domain-containing protein-
PE064_RS05165 (PE064_05165)1062451..1063359+909WP_271250891.1HNH endonuclease-
PE064_RS05170 (PE064_05170)1063349..1063918-570WP_271250892.1transposase-
PE064_RS05175 (PE064_05175)1064038..1065135-1098WP_271250893.1crosslink repair DNA glycosylase YcaQ family protein-
PE064_RS05180 (PE064_05180)1065175..1065387-213WP_271250894.1type II toxin-antitoxin system HicB family antitoxinAntitoxin
PE064_RS05185 (PE064_05185)1065393..1065587-195WP_271250895.1type II toxin-antitoxin system HicA family toxinToxin
PE064_RS05190 (PE064_05190)1065678..1068371-2694WP_271250896.1pyruvate dehydrogenase (acetyl-transferring), homodimeric type-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(6-62)

Antitoxin

HicB-like antitoxin of toxin-antitoxin system

(3-62)


Sequences

Toxin        


Download         Length: 65 a.a.        Molecular weight: 6854.93 Da        Isoelectric Point: 11.6952

>T267613 WP_271250895.1 NZ_CP116007:c1065587-1065393 [Pseudoxanthomonas mexicana]
VPPKIRDVLQQLKDAGWQQVGQTGSRRQFKHPTLPGRVTVAGKPGDDVAPGTLGSILKQAGIKR

Download         Length: 195 bp

Antitoxin


Download         Length: 71 a.a.        Molecular weight: 7316.36 Da        Isoelectric Point: 4.1511

>AT267613 WP_271250894.1 NZ_CP116007:c1065387-1065175 [Pseudoxanthomonas mexicana]
MRYAIVIEQAGGNYSAYVPDLPGCVATGATKAEVEALIHDAIALHLAGMREDGLAIPMPSSQVEYIDVAA

Download         Length: 213 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References