Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 3970073..3970610 Replicon chromosome
Accession NZ_CP116005
Organism Sphingosinicella microcystinivorans strain DMF-3

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag PE061_RS19165 Protein ID WP_271256806.1
Coordinates 3970073..3970375 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag PE061_RS19170 Protein ID WP_271256807.1
Coordinates 3970365..3970610 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PE061_RS19145 (PE061_19145) 3965290..3966783 + 1494 WP_271256802.1 amidase -
PE061_RS19150 (PE061_19150) 3966797..3967183 + 387 WP_271256803.1 arsenate reductase family protein -
PE061_RS19155 (PE061_19155) 3967219..3969762 + 2544 WP_271256804.1 type I DNA topoisomerase -
PE061_RS19160 (PE061_19160) 3969768..3969947 + 180 WP_271256805.1 hypothetical protein -
PE061_RS19165 (PE061_19165) 3970073..3970375 - 303 WP_271256806.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PE061_RS19170 (PE061_19170) 3970365..3970610 - 246 WP_271256807.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
PE061_RS19175 (PE061_19175) 3970770..3971087 + 318 WP_271256808.1 quaternary ammonium compound efflux SMR transporter SugE -
PE061_RS19180 (PE061_19180) 3971128..3973338 + 2211 WP_271256809.1 ribonuclease R -
PE061_RS19185 (PE061_19185) 3973355..3973603 - 249 WP_271256810.1 Hpt domain-containing protein -
PE061_RS19190 (PE061_19190) 3973773..3973940 + 168 WP_046348982.1 50S ribosomal protein L33 -
PE061_RS19195 (PE061_19195) 3973962..3974324 - 363 WP_271256811.1 response regulator -
PE061_RS19200 (PE061_19200) 3974429..3974707 + 279 WP_271256812.1 DUF3572 domain-containing protein -
PE061_RS19205 (PE061_19205) 3974704..3975315 + 612 WP_271256813.1 HAD family hydrolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(9-94)

Antitoxin

Antitoxin ParD

(1-80)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11200.65 Da        Isoelectric Point: 6.8805

>T267611 WP_271256806.1 NZ_CP116005:c3970375-3970073 [Sphingosinicella microcystinivorans]
MAGRRGGFRLTPRAEADLEDIFTYTAERWSLMQAEDHHAGFAAAFEKLGSGERSGRAAGVPGAYLKYAVGSHLVFYREPE
SEIIVVRVLHQRMDVGRYLE

Download         Length: 303 bp

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8776.75 Da        Isoelectric Point: 8.8335

>AT267611 WP_271256807.1 NZ_CP116005:c3970610-3970365 [Sphingosinicella microcystinivorans]
MARNTSISLGDHFSGFIETQVSSGRYGSASDVVRAGLRLLEEREARVRALQAALAEGEASGEPRPFDNTAFLNRMRARHG
G

Download         Length: 246 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References