Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 3964610..3965160 Replicon chromosome
Accession NZ_CP116005
Organism Sphingosinicella microcystinivorans strain DMF-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PE061_RS19135 Protein ID WP_271256800.1
Coordinates 3964610..3964900 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PE061_RS19140 Protein ID WP_271256801.1
Coordinates 3964897..3965160 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PE061_RS19105 (PE061_19105) 3960451..3960864 - 414 WP_271256795.1 VOC family protein -
PE061_RS19110 (PE061_19110) 3960953..3961135 - 183 WP_271256796.1 CsbD family protein -
PE061_RS19115 (PE061_19115) 3961227..3962204 - 978 WP_271256797.1 sulfur carrier protein ThiS -
PE061_RS19120 (PE061_19120) 3962312..3962752 + 441 WP_271256798.1 type II 3-dehydroquinate dehydratase -
PE061_RS19125 (PE061_19125) 3962809..3963252 + 444 WP_271259252.1 acetyl-CoA carboxylase biotin carboxyl carrier protein -
PE061_RS19130 (PE061_19130) 3963254..3964606 + 1353 WP_271256799.1 acetyl-CoA carboxylase biotin carboxylase subunit -
PE061_RS19135 (PE061_19135) 3964610..3964900 - 291 WP_271256800.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PE061_RS19140 (PE061_19140) 3964897..3965160 - 264 WP_271256801.1 ribbon-helix-helix domain-containing protein Antitoxin
PE061_RS19145 (PE061_19145) 3965290..3966783 + 1494 WP_271256802.1 amidase -
PE061_RS19150 (PE061_19150) 3966797..3967183 + 387 WP_271256803.1 arsenate reductase family protein -
PE061_RS19155 (PE061_19155) 3967219..3969762 + 2544 WP_271256804.1 type I DNA topoisomerase -
PE061_RS19160 (PE061_19160) 3969768..3969947 + 180 WP_271256805.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(6-43)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11166.88 Da        Isoelectric Point: 10.4120

>T267610 WP_271256800.1 NZ_CP116005:c3964900-3964610 [Sphingosinicella microcystinivorans]
MKILWTSKASGDLARLFEFLKPVAPDAAARVIRGLVNAPDRLLAWPRIGERHDAYAPREVRRIIVGNYEMRYEVRDTEIV
VLRVWHTRENRNPTGE

Download         Length: 291 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9669.92 Da        Isoelectric Point: 4.8259

>AT267610 WP_271256801.1 NZ_CP116005:c3965160-3964897 [Sphingosinicella microcystinivorans]
MSTRVLTAHVPVDLAEKVDSVAARLERSRGWVVKQALAAWVDQEEERHRLTLEALADVDAGRLVDHQSMRDWAESLETVS
PLSPPVA

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References