Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2946317..2946876 Replicon chromosome
Accession NZ_CP116005
Organism Sphingosinicella microcystinivorans strain DMF-3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PE061_RS14105 Protein ID WP_271255891.1
Coordinates 2946583..2946876 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PE061_RS14100 Protein ID WP_271255890.1
Coordinates 2946317..2946586 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PE061_RS14065 (PE061_14065) 2942091..2942975 - 885 WP_271255883.1 replication initiator protein A -
PE061_RS14070 (PE061_14070) 2942972..2943238 - 267 WP_271255884.1 helix-turn-helix domain-containing protein -
PE061_RS14075 (PE061_14075) 2943368..2944003 - 636 WP_271255885.1 DUF2285 domain-containing protein -
PE061_RS14080 (PE061_14080) 2943930..2944133 - 204 WP_271255886.1 DUF6499 domain-containing protein -
PE061_RS14085 (PE061_14085) 2944285..2944551 - 267 WP_271255887.1 DUF2285 domain-containing protein -
PE061_RS14090 (PE061_14090) 2945057..2945281 - 225 WP_271255888.1 hypothetical protein -
PE061_RS14095 (PE061_14095) 2945341..2945988 - 648 WP_271255889.1 DNA methyltransferase -
PE061_RS14100 (PE061_14100) 2946317..2946586 + 270 WP_271255890.1 ribbon-helix-helix domain-containing protein Antitoxin
PE061_RS14105 (PE061_14105) 2946583..2946876 + 294 WP_271255891.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PE061_RS14110 (PE061_14110) 2947008..2947208 - 201 WP_271255892.1 hypothetical protein -
PE061_RS14115 (PE061_14115) 2947209..2947871 - 663 WP_271255893.1 hypothetical protein -
PE061_RS14120 (PE061_14120) 2948066..2948278 - 213 WP_271255894.1 hypothetical protein -
PE061_RS14130 (PE061_14130) 2949045..2949323 - 279 WP_271255895.1 BolA family protein -
PE061_RS14135 (PE061_14135) 2949377..2950228 - 852 WP_271255896.1 type II CAAX endopeptidase family protein -
PE061_RS14140 (PE061_14140) 2950361..2950948 + 588 WP_271255897.1 J domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11427.00 Da        Isoelectric Point: 6.8714

>T267609 WP_271255891.1 NZ_CP116005:2946583-2946876 [Sphingosinicella microcystinivorans]
MRIQWTTKASSDLVRLHDHLSPVAPDAAARVVQQLAHAPDRLLDYPRIGEKLEAYEPREVRRIIVGDYELRYEIASATIF
ILRLWHCRENRRFDSED

Download         Length: 294 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9797.27 Da        Isoelectric Point: 5.6016

>AT267609 WP_271255890.1 NZ_CP116005:2946317-2946586 [Sphingosinicella microcystinivorans]
MATDTKVLTAHVPLGLAEKVDSMAARLERSRGWVMKQALAAWVDLEEERHRMTLEALADVDAGRVIDHQAIQAWADSLGT
DKPLPPPVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References