Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 3297960..3299680 | Replicon | chromosome |
| Accession | NZ_CP116004 | ||
| Organism | Edwardsiella piscicida strain CC2 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | A0A411H3H5 |
| Locus tag | PED70_RS15195 | Protein ID | WP_015683486.1 |
| Coordinates | 3299024..3299680 (-) | Length | 219 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | - |
| Locus tag | PED70_RS15190 | Protein ID | WP_041692662.1 |
| Coordinates | 3297960..3299027 (-) | Length | 356 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| PED70_RS15180 (PED70_15180) | 3293985..3294701 | - | 717 | WP_012849890.1 | SprT family zinc-dependent metalloprotease | - |
| PED70_RS15185 (PED70_15185) | 3294701..3297796 | - | 3096 | WP_012849889.1 | HsdR family type I site-specific deoxyribonuclease | - |
| PED70_RS15190 (PED70_15190) | 3297960..3299027 | - | 1068 | WP_041692662.1 | macro domain-containing protein | Antitoxin |
| PED70_RS15195 (PED70_15195) | 3299024..3299680 | - | 657 | WP_015683486.1 | DUF4433 domain-containing protein | Toxin |
| PED70_RS15200 (PED70_15200) | 3299693..3301042 | - | 1350 | WP_080545142.1 | restriction endonuclease subunit S | - |
| PED70_RS15205 (PED70_15205) | 3301054..3303492 | - | 2439 | WP_015683488.1 | type I restriction-modification system subunit M | - |
| PED70_RS15210 (PED70_15210) | 3303531..3303770 | - | 240 | WP_012849883.1 | hypothetical protein | - |
| PED70_RS15215 (PED70_15215) | 3304122..3304478 | - | 357 | Protein_2936 | integrase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 219 a.a. Molecular weight: 25046.43 Da Isoelectric Point: 6.9045
>T267607 WP_015683486.1 NZ_CP116004:c3299680-3299024 [Edwardsiella piscicida]
MAYDYSASLNPQKALIWRIVHRDNIPWILDNGLHCGNSQVQAVNWINIGNPELIGKRAGHPVPVGTGGTLHDYVPFYFTP
FSPMLMNIHSGRGGITQRPNEEIVILVSSLRSVAAQNAPFVFTDSHAYYNWANYYTRLEDLNQIDWSILQARDFRRDPDD
PAKFERYQAEALIWQHCPITLLVGMICYNDGVRLQLEQWLSQRNLTMPVHARAGWYFS
MAYDYSASLNPQKALIWRIVHRDNIPWILDNGLHCGNSQVQAVNWINIGNPELIGKRAGHPVPVGTGGTLHDYVPFYFTP
FSPMLMNIHSGRGGITQRPNEEIVILVSSLRSVAAQNAPFVFTDSHAYYNWANYYTRLEDLNQIDWSILQARDFRRDPDD
PAKFERYQAEALIWQHCPITLLVGMICYNDGVRLQLEQWLSQRNLTMPVHARAGWYFS
Download Length: 657 bp
Antitoxin
Download Length: 356 a.a. Molecular weight: 40668.02 Da Isoelectric Point: 6.9067
>AT267607 WP_041692662.1 NZ_CP116004:c3299027-3297960 [Edwardsiella piscicida]
MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYAHACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKKVRSIAIPPLGAGNGGLNWPDVRARIESALGDLQDTEILIYEPTEKYQNVAKSS
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNSEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGQCQPTLDSVKEG
LHQWPAGEPWASRKIKLFDDKNLQFAINRVMEFHC
MITYTQGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMKAYAHACKQKQVMTGKMFITETGELMGPRWIVNFPTK
QHWRADSRMAWIEDGLQDLRRFLIEKKVRSIAIPPLGAGNGGLNWPDVRARIESALGDLQDTEILIYEPTEKYQNVAKSS
GVKKLTPARAMIAELVRRYWVLGMECSLLEIQKLAWLLQRAIELHQQEDVLKLRFEAHYYGPYAPNLNHLLNALDGTYLK
AEKRIPDSQPLDVIWFNDREKEHINLWLNSEAKAWLPALEQVSQLIDGFESPFGLELLATVDWLLTRGQCQPTLDSVKEG
LHQWPAGEPWASRKIKLFDDKNLQFAINRVMEFHC
Download Length: 1068 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|