Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 1714324..1714846 Replicon chromosome
Accession NZ_CP116004
Organism Edwardsiella piscicida strain CC2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PED70_RS07905 Protein ID WP_069578568.1
Coordinates 1714324..1714605 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A411H7D8
Locus tag PED70_RS07910 Protein ID WP_069578569.1
Coordinates 1714595..1714846 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PED70_RS07890 (PED70_07890) 1709710..1710486 + 777 WP_073382315.1 hypothetical protein -
PED70_RS07895 (PED70_07895) 1710479..1712140 + 1662 WP_165362063.1 terminase -
PED70_RS07900 (PED70_07900) 1712137..1714251 + 2115 WP_129986139.1 portal protein -
PED70_RS07905 (PED70_07905) 1714324..1714605 - 282 WP_069578568.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PED70_RS07910 (PED70_07910) 1714595..1714846 - 252 WP_069578569.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PED70_RS07915 (PED70_07915) 1715124..1716125 + 1002 WP_129986135.1 hypothetical protein -
PED70_RS07920 (PED70_07920) 1716143..1717381 + 1239 WP_280977425.1 N4-gp56 family major capsid protein -
PED70_RS07925 (PED70_07925) 1717440..1717835 + 396 WP_080783446.1 hypothetical protein -
PED70_RS07930 (PED70_07930) 1717877..1718320 + 444 WP_080783445.1 hypothetical protein -
PED70_RS07935 (PED70_07935) 1718386..1718901 + 516 WP_236721582.1 hypothetical protein -
PED70_RS07940 (PED70_07940) 1718901..1719563 + 663 WP_109579934.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1676447..1737917 61470


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-84)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10738.62 Da        Isoelectric Point: 10.6993

>T267600 WP_069578568.1 NZ_CP116004:c1714605-1714324 [Edwardsiella piscicida]
MTYKLSFEKRALKEWKKLAPPIQSQLKKKLIERLENPHIPAARLSGRANRYKIKLRSSGYRLVYEVNDSEIILLVIAIGK
RADNDVYLAADGR

Download         Length: 282 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9154.26 Da        Isoelectric Point: 3.8074

>AT267600 WP_069578569.1 NZ_CP116004:c1714846-1714595 [Edwardsiella piscicida]
MAYQILTTTAASITDLKRNPMGTIAEGDGNAVAILNRNEPAFYCVPPELYAYYLELAENAALNRIADERLEDAEFVSVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A411H7D8

References