Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 3168857..3169520 Replicon chromosome
Accession NZ_CP116003
Organism Edwardsiella piscicida strain CC1

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag PED68_RS14650 Protein ID WP_045474345.1
Coordinates 3168857..3169225 (-) Length 123 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID D0ZDY6
Locus tag PED68_RS14655 Protein ID WP_012849755.1
Coordinates 3169254..3169520 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PED68_RS14630 (PED68_14630) 3164788..3166521 - 1734 WP_012849750.1 single-stranded-DNA-specific exonuclease RecJ -
PED68_RS14635 (PED68_14635) 3166526..3167242 - 717 WP_012849751.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PED68_RS14640 (PED68_14640) 3167270..3168169 - 900 WP_012849752.1 site-specific tyrosine recombinase XerD -
PED68_RS14645 (PED68_14645) 3168320..3168832 + 513 WP_012849753.1 flavodoxin FldB -
PED68_RS14650 (PED68_14650) 3168857..3169225 - 369 WP_045474345.1 protein YgfX Toxin
PED68_RS14655 (PED68_14655) 3169254..3169520 - 267 WP_012849755.1 FAD assembly factor SdhE Antitoxin
PED68_RS14660 (PED68_14660) 3169874..3170872 + 999 WP_012849756.1 tRNA-modifying protein YgfZ -
PED68_RS14665 (PED68_14665) 3170915..3171739 - 825 WP_012849757.1 shikimate 5-dehydrogenase -
PED68_RS14670 (PED68_14670) 3171898..3172770 - 873 WP_012849758.1 nucleoside-specific channel-forming protein Tsx -
PED68_RS14675 (PED68_14675) 3173379..3174029 + 651 WP_015462279.1 hemolysin III family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-115)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 123 a.a.        Molecular weight: 14248.71 Da        Isoelectric Point: 11.3493

>T267597 WP_045474345.1 NZ_CP116003:c3169225-3168857 [Edwardsiella piscicida]
MFLLGHGALVLAILLAPWPENYSVFWLILLVAVIFECIRSQRRIARNRGELQLLAPQVWHWQLREWRLARRPWVSDLGAL
LILQSTHGAPCRRRLWLAADSMSREEWGQLRRTLLDAGDDRA

Download         Length: 369 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10318.90 Da        Isoelectric Point: 5.6951

>AT267597 WP_012849755.1 NZ_CP116003:c3169520-3169254 [Edwardsiella piscicida]
MDINNKARVHWACRRGMRELDIAIMPFFEHEYDALNDADKQTFVRLLACDDPELFKWLMNQGKPDDADLARMITLIQTRN
KERGPLAL

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A034T2Q8

References