Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 2149640..2150115 Replicon chromosome
Accession NZ_CP115960
Organism Sphingomonas sp. 7/4-4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PIB19_RS10820 Protein ID WP_271240821.1
Coordinates 2149640..2149963 (-) Length 108 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PIB19_RS10825 Protein ID WP_271240822.1
Coordinates 2149960..2150115 (-) Length 52 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PIB19_RS10795 (PIB19_10795) 2146071..2146318 + 248 Protein_2134 hypothetical protein -
PIB19_RS10800 (PIB19_10800) 2146427..2147377 + 951 WP_271240965.1 hypothetical protein -
PIB19_RS10805 (PIB19_10805) 2147313..2148194 + 882 WP_271240818.1 hypothetical protein -
PIB19_RS10810 (PIB19_10810) 2148164..2148589 + 426 WP_271240819.1 ATP-binding cassette domain-containing protein -
PIB19_RS10815 (PIB19_10815) 2148593..2149615 + 1023 WP_271240820.1 DUF4238 domain-containing protein -
PIB19_RS10820 (PIB19_10820) 2149640..2149963 - 324 WP_271240821.1 DUF5615 family PIN-like protein Toxin
PIB19_RS10825 (PIB19_10825) 2149960..2150115 - 156 WP_271240822.1 DUF433 domain-containing protein Antitoxin
PIB19_RS10830 (PIB19_10830) 2150299..2150475 + 177 WP_271240823.1 stability determinant -
PIB19_RS10835 (PIB19_10835) 2151981..2152388 + 408 WP_271240966.1 DUF3597 domain-containing protein -
PIB19_RS10840 (PIB19_10840) 2152882..2153115 + 234 WP_271240824.1 hypothetical protein -
PIB19_RS10845 (PIB19_10845) 2153368..2153580 + 213 WP_077509887.1 cold-shock protein -
PIB19_RS10850 (PIB19_10850) 2153653..2153865 + 213 WP_271240825.1 hypothetical protein -
PIB19_RS10855 (PIB19_10855) 2153998..2154147 + 150 WP_271240826.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(1-74)

Antitoxin

Protein of unknown function DUF433

(1-38)


Sequences

Toxin        


Download         Length: 108 a.a.        Molecular weight: 11984.73 Da        Isoelectric Point: 4.4279

>T267554 WP_271240821.1 NZ_CP115960:c2149963-2149640 [Sphingomonas sp. 7/4-4]
MNFLIDAQLPPALCGWLRERGHQAVHVFEIGMVAASDAEIAARAEADGAVLVSKDEDFVTLRLPDRFMFVWLRCGNTTNR
ALAAWLEARWEQVEALLEAGELFVEAR

Download         Length: 324 bp

Antitoxin


Download         Length: 52 a.a.        Molecular weight: 5255.89 Da        Isoelectric Point: 3.7696

>AT267554 WP_271240822.1 NZ_CP115960:c2150115-2149960 [Sphingomonas sp. 7/4-4]
VRVTDVLEMLAGGASPAEIAGDFPYLSEDDVRAVLAYAAAQADHPVVLAAE

Download         Length: 156 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References