Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 910038..910699 Replicon chromosome
Accession NZ_CP115957
Organism Ralstonia pseudosolanacearum strain PSS4

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PG908_RS04455 Protein ID WP_013211023.1
Coordinates 910038..910451 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID Q8Y121
Locus tag PG908_RS04460 Protein ID WP_011000825.1
Coordinates 910448..910699 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG908_RS04430 905424..905624 + 201 WP_226951801.1 hypothetical protein -
PG908_RS04435 905599..906243 + 645 WP_064477634.1 DUF6441 family protein -
PG908_RS04440 906286..906576 - 291 WP_011000820.1 H-NS family nucleoid-associated regulatory protein -
PG908_RS04445 906762..908228 - 1467 WP_247548542.1 YopJ family acetyltransferase -
PG908_RS04450 908839..909966 + 1128 WP_193032737.1 DNA cytosine methyltransferase -
PG908_RS04455 910038..910451 - 414 WP_013211023.1 type II toxin-antitoxin system VapC family toxin Toxin
PG908_RS04460 910448..910699 - 252 WP_011000825.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PG908_RS04465 910779..914879 + 4101 WP_247548543.1 tape measure protein -
PG908_RS04470 914885..915280 + 396 WP_011000827.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 865290..924303 59013


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-124)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15605.94 Da        Isoelectric Point: 5.7557

>T267550 WP_013211023.1 NZ_CP115957:c910451-910038 [Ralstonia pseudosolanacearum]
MSYLIDTNVLSELRRKAPDARVVAWMQDRPRQSLYLSVLTLGEIRKGIERLEDAVRRQNLIDWLEVELPNYFLGRLLDID
AHTADRWGRLMSSAGRPLPAIDGLLAATALQHDLTLVTRNTKDFAGLDVQLINPWEA

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9335.52 Da        Isoelectric Point: 5.0774

>AT267550 WP_011000825.1 NZ_CP115957:c910699-910448 [Ralstonia pseudosolanacearum]
MQSWQMQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGSGESLVSFMRQSPLADQDDVVFERERSLPRE
VEF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q8Y121

References