Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/COG3657-dnstrm_HI1420
Location 68805..69415 Replicon plasmid pmega
Accession NZ_CP115956
Organism Ralstonia pseudosolanacearum strain RUN2340

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG907_RS18210 Protein ID WP_193029203.1
Coordinates 69107..69415 (-) Length 103 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PG907_RS18205 Protein ID WP_016722339.1
Coordinates 68805..69110 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG907_RS18185 65162..65872 + 711 Protein_57 IS5 family transposase -
PG907_RS18190 65932..66917 + 986 WP_193025998.1 IS630 family transposase -
PG907_RS18195 66922..67083 + 162 WP_193029856.1 hypothetical protein -
PG907_RS18200 67279..68592 - 1314 WP_193029205.1 MFS family transporter -
PG907_RS18205 68805..69110 - 306 WP_016722339.1 putative addiction module antidote protein Antitoxin
PG907_RS18210 69107..69415 - 309 WP_193029203.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG907_RS18215 69491..70690 - 1200 WP_275761100.1 MFS transporter -
PG907_RS18220 70817..71632 - 816 WP_275761101.1 GntR family transcriptional regulator -
PG907_RS18225 71810..72361 - 552 WP_275761102.1 helix-turn-helix domain-containing protein -
PG907_RS18230 72494..73087 + 594 WP_275761103.1 GNAT family N-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cyaB / flgC / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..1973144 1973144


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(3-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(52-96)


Sequences

Toxin        


Download         Length: 103 a.a.        Molecular weight: 11783.57 Da        Isoelectric Point: 7.1355

>T267548 WP_193029203.1 NZ_CP115956:c69415-69107 [Ralstonia pseudosolanacearum]
MLTIRTTEIFDDWFCSLRDKAAQRRIQVRIDRLQMGNPGDMKAVRDGIRELRIDHGPGYRLYVVQHGVVLIVLLCGGDKS
TQEADIRRAIDLSRRLDVDDME

Download         Length: 309 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 10967.57 Da        Isoelectric Point: 7.2780

>AT267548 WP_016722339.1 NZ_CP115956:c69110-68805 [Ralstonia pseudosolanacearum]
MTMAQRTIKTRPWDSAEHLRTEADIAAYLDACLEEAGDDPAFITHALGVVARSRGMTQLARETGMTREGLYKALSEGGNP
SFATVLKVIRALGIRLHAVPT

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References