Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 3541193..3541854 Replicon chromosome
Accession NZ_CP115955
Organism Ralstonia pseudosolanacearum strain RUN2340

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PG907_RS16710 Protein ID WP_193026209.1
Coordinates 3541441..3541854 (+) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID D8N5P4
Locus tag PG907_RS16705 Protein ID WP_020749302.1
Coordinates 3541193..3541444 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG907_RS16695 3536616..3537011 - 396 WP_197366418.1 hypothetical protein -
PG907_RS16700 3537017..3541117 - 4101 WP_275760264.1 tape measure protein -
PG907_RS16705 3541193..3541444 + 252 WP_020749302.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PG907_RS16710 3541441..3541854 + 414 WP_193026209.1 type II toxin-antitoxin system VapC family toxin Toxin
PG907_RS16715 3541999..3543081 - 1083 WP_275760435.1 DNA cytosine methyltransferase -
PG907_RS16720 3543821..3544111 + 291 WP_275760436.1 H-NS family nucleoid-associated regulatory protein -
PG907_RS16725 3544155..3544799 - 645 WP_193035574.1 DUF6441 family protein -
PG907_RS16730 3544774..3544941 - 168 WP_275760438.1 hypothetical protein -
PG907_RS16735 3544992..3545384 - 393 WP_275760439.1 hypothetical protein -
PG907_RS16740 3545393..3546163 - 771 WP_275760440.1 hypothetical protein -
PG907_RS16745 3546296..3546742 - 447 WP_197366474.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3527474..3577240 49766


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15742.09 Da        Isoelectric Point: 6.2337

>T267547 WP_193026209.1 NZ_CP115955:3541441-3541854 [Ralstonia pseudosolanacearum]
MSYLIDTNVLSELRRKQPDARVLAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLETELPNYFLGRLLDVD
AHTADRWGRLMSSANRPLPAIDGLLAATALQHDLILVTRNTKDFVGLDVPLINPWET

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9258.46 Da        Isoelectric Point: 5.0628

>AT267547 WP_020749302.1 NZ_CP115955:3541193-3541444 [Ralstonia pseudosolanacearum]
MQSWQLQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGSGESLVDFMRQSPLAGLDDVVFERERSLPRE
VDF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A5B7U0Z6

References