Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN-MazE
Location 3360575..3361208 Replicon chromosome
Accession NZ_CP115955
Organism Ralstonia pseudosolanacearum strain RUN2340

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag PG907_RS15915 Protein ID WP_193027353.1
Coordinates 3360575..3360988 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID D8N529
Locus tag PG907_RS15920 Protein ID WP_020747258.1
Coordinates 3360975..3361208 (-) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG907_RS15890 3356079..3357656 + 1578 WP_193027360.1 glycerol-3-phosphate dehydrogenase -
PG907_RS15895 3357913..3358035 + 123 Protein_3114 ABC transporter -
PG907_RS15900 3358036..3358263 + 228 Protein_3115 carbohydrate ABC transporter substrate-binding protein -
PG907_RS15905 3358431..3359927 + 1497 WP_193027357.1 glycerol kinase GlpK -
PG907_RS15910 3359971..3360600 + 630 WP_193027355.1 DUF1415 family protein -
PG907_RS15915 3360575..3360988 - 414 WP_193027353.1 PIN domain-containing protein Toxin
PG907_RS15920 3360975..3361208 - 234 WP_020747258.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
PG907_RS15925 3361265..3362872 - 1608 WP_193028416.1 glucan biosynthesis protein -
PG907_RS15930 3363094..3364326 + 1233 WP_193027350.1 AGE family epimerase/isomerase -
PG907_RS15935 3364334..3365629 + 1296 WP_193027348.1 MFS transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(7-116)

Antitoxin

SpoVT-AbrB domain

(5-39)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15091.41 Da        Isoelectric Point: 5.5407

>T267546 WP_193027353.1 NZ_CP115955:c3360988-3360575 [Ralstonia pseudosolanacearum]
MPATEAFFDSNVVLYLLSADAAKADTAETLLMTGGVVSVQVLNETTHVMRRKLAMPWHAIETVQEAVRAQCRIEPLTLET
HELGRRLAERYGLSVYDALIVAAALLAGCNVLYSEDMQHGLVVEQHLRIVNPFSARA

Download         Length: 414 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8806.98 Da        Isoelectric Point: 8.7287

>AT267546 WP_020747258.1 NZ_CP115955:c3361208-3360975 [Ralstonia pseudosolanacearum]
MQVSKWGNSLAIRLPAAVVEALQLHEGDDVEVVIAGERSFGVRRKRSARELFDRIHQYRGKLPADFIFERDQANARD

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A0S4TW23

References