Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 2628212..2628756 Replicon chromosome
Accession NZ_CP115955
Organism Ralstonia pseudosolanacearum strain RUN2340

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag PG907_RS12350 Protein ID WP_193027890.1
Coordinates 2628481..2628756 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag PG907_RS12345 Protein ID WP_193027891.1
Coordinates 2628212..2628481 (+) Length 90 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG907_RS12315 2623496..2624065 - 570 WP_275760282.1 LysR substrate-binding domain-containing protein -
PG907_RS12320 2624153..2624941 - 789 WP_193027111.1 IS21-like element ISRso19 family helper ATPase IstB -
PG907_RS12325 2624938..2625954 - 1017 WP_193027114.1 IS21 family transposase -
PG907_RS12330 2625995..2626357 - 363 WP_247664447.1 LysR family transcriptional regulator -
PG907_RS12335 2626489..2627268 + 780 WP_193027892.1 alpha/beta hydrolase -
PG907_RS12340 2627459..2628046 + 588 WP_230642671.1 NAD(P)H-dependent oxidoreductase -
PG907_RS12345 2628212..2628481 + 270 WP_193027891.1 ribbon-helix-helix domain-containing protein Antitoxin
PG907_RS12350 2628481..2628756 + 276 WP_193027890.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG907_RS12355 2628841..2629826 + 986 WP_193025998.1 IS630 family transposase -
PG907_RS12360 2629900..2630460 + 561 WP_193027889.1 DUF2726 domain-containing protein -
PG907_RS12365 2630438..2631001 - 564 WP_193027888.1 recombinase family protein -
PG907_RS12375 2631225..2632541 - 1317 WP_193027887.1 serine--tRNA ligase -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside IScluster/Tn - - 2619534..2629826 10292


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 92 a.a.        Molecular weight: 10630.33 Da        Isoelectric Point: 10.1779

>T267545 WP_193027890.1 NZ_CP115955:2628481-2628756 [Ralstonia pseudosolanacearum]
MEVKWTGKAVSDITRLYEFLSQVNKPAAIRVVQSLTGAPKSLVVNPRIGEQLDEFEPREVRRIIVGQYEMRYAIRGSVIY
VLRLWHTREDR

Download         Length: 276 bp


Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10056.37 Da        Isoelectric Point: 6.7268

>AT267545 WP_193027891.1 NZ_CP115955:2628212-2628481 [Ralstonia pseudosolanacearum]
MAHLDTRVLTAHVPVQLAERVDQIAERLERSRGWIMKQALSAWIDQEEERSRLTREALADVDAGTVIDHQAVQAWADSLS
TSKPKKAPR

Download         Length: 270 bp


Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References