Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1041674..1042218 Replicon plasmid pmega
Accession NZ_CP115953
Organism Ralstonia solanacearum CFBP2957

Toxin (Protein)


Gene name relE Uniprot ID D8P457
Locus tag PG903_RS20620 Protein ID WP_013208202.1
Coordinates 1041943..1042218 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID D8P456
Locus tag PG903_RS20615 Protein ID WP_013208201.1
Coordinates 1041674..1041943 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG903_RS20585 1037172..1038050 - 879 WP_013208194.1 EamA family transporter -
PG903_RS20590 1038262..1038438 + 177 WP_013208195.1 hypothetical protein -
PG903_RS20595 1038438..1038575 + 138 WP_231107412.1 hypothetical protein -
PG903_RS20600 1038709..1039092 + 384 WP_042591092.1 hypothetical protein -
PG903_RS20605 1039316..1040356 + 1041 WP_013208198.1 AvrPphF family type III effector -
PG903_RS20610 1040396..1041292 - 897 WP_039555871.1 LysR substrate-binding domain-containing protein -
PG903_RS20615 1041674..1041943 + 270 WP_013208201.1 ribbon-helix-helix domain-containing protein Antitoxin
PG903_RS20620 1041943..1042218 + 276 WP_013208202.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PG903_RS20625 1042468..1042833 + 366 Protein_885 SMP-30/gluconolactonase/LRE family protein -
PG903_RS20630 1042882..1043742 - 861 WP_013208204.1 spermidine synthase -
PG903_RS20635 1044031..1044966 + 936 WP_013208205.1 5-dehydro-4-deoxyglucarate dehydratase -
PG903_RS20640 1044998..1046584 + 1587 WP_013208206.1 aldehyde dehydrogenase (NADP(+)) -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2210741 2210741


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(9-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10806.56 Da        Isoelectric Point: 9.5036

>T267540 WP_013208202.1 NZ_CP115953:1041943-1042218 [Ralstonia solanacearum CFBP2957]
MELKWTSKALSDVARLYEFLAPVNKPAAARTVQALIKAPTILLTNPRVGEQLFQFEPREVRRMLVGQYEMRYELQDETIY
VLRLWHTREDR

Download         Length: 276 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 10020.29 Da        Isoelectric Point: 4.8616

>AT267540 WP_013208201.1 NZ_CP115953:1041674-1041943 [Ralstonia solanacearum CFBP2957]
MPKAETRVLTAHVPVPLAEKVDQLAERLERSRGWIMKQALSAWIGQEEERDRLTHEALADVDGGRVIDHQAVQAWADSLS
TDEPLQVPR

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A177RHM3

Antitoxin

Source ID Structure
AlphaFold DB A0A177RGQ6

References