Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 747187..747848 Replicon plasmid pmega
Accession NZ_CP115953
Organism Ralstonia solanacearum CFBP2957

Toxin (Protein)


Gene name vapC Uniprot ID A0A399W071
Locus tag PG903_RS19375 Protein ID WP_003278076.1
Coordinates 747187..747600 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag PG903_RS19380 Protein ID WP_003278075.1
Coordinates 747597..747848 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG903_RS19335 742245..742637 + 393 WP_275719466.1 hypothetical protein -
PG903_RS19340 742634..742855 + 222 WP_275719467.1 hypothetical protein -
PG903_RS19345 742830..743474 + 645 WP_275719468.1 DUF6441 family protein -
PG903_RS19350 743517..743807 - 291 WP_247590003.1 H-NS family nucleoid-associated regulatory protein -
PG903_RS19355 744255..745138 + 884 Protein_631 IS5 family transposase -
PG903_RS19360 745375..745998 + 624 WP_275719469.1 hypothetical protein -
PG903_RS19365 746237..746728 + 492 Protein_633 IS5 family transposase -
PG903_RS19370 746943..747140 + 198 Protein_634 DNA cytosine methyltransferase -
PG903_RS19375 747187..747600 - 414 WP_003278076.1 type II toxin-antitoxin system VapC family toxin Toxin
PG903_RS19380 747597..747848 - 252 WP_003278075.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
PG903_RS19385 747923..752023 + 4101 WP_275719470.1 tape measure protein -
PG903_RS19390 752027..752422 + 396 WP_275719471.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - cheY / cyaB / flgG / fliM / fliI / acrB / adeG / cheY / cheB / cheW / motA 1..2210741 2210741


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-122)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-63)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 15756.12 Da        Isoelectric Point: 6.2337

>T267539 WP_003278076.1 NZ_CP115953:c747600-747187 [Ralstonia solanacearum CFBP2957]
MSYLIDTNVLSELRRKQPDARVLAWMQDRPRQSLYLSVLTLGEIRKGIERLDDAARRQHLIDWLETELPNYFLGRLLDID
AHTADRWGRLMSSANRPLPAIDGLLAATALQHDLILVTRNTKDFVGLDVPLINPWET

Download         Length: 414 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9242.46 Da        Isoelectric Point: 5.0774

>AT267539 WP_003278075.1 NZ_CP115953:c747848-747597 [Ralstonia solanacearum CFBP2957]
MQSWQLQAAKARFSDVVKRAADDGPQEITVHGRPVAVVISRALFDRLSGGGESLVDFMRQSPLAGLDDVVFERERSLPRE
VEF

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A399W071

Antitoxin

Source ID Structure

References