Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 1099079..1099668 Replicon chromosome
Accession NZ_CP115952
Organism Ralstonia solanacearum CFBP2957

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag PG903_RS05340 Protein ID WP_013206420.1
Coordinates 1099414..1099668 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag PG903_RS05335 Protein ID WP_013206421.1
Coordinates 1099079..1099417 (-) Length 113 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PG903_RS05305 1095284..1095622 + 339 WP_013206427.1 phage tail protein -
PG903_RS05310 1095715..1096296 + 582 WP_275719037.1 phage tail protein -
PG903_RS05315 1096302..1096898 + 597 WP_013206425.1 tail fiber assembly protein -
PG903_RS05320 1096895..1097596 + 702 WP_013206424.1 phage minor tail protein L -
PG903_RS05325 1097598..1098308 + 711 WP_013206423.1 C40 family peptidase -
PG903_RS05330 1098312..1098914 + 603 WP_043908480.1 tail assembly protein -
PG903_RS05335 1099079..1099417 - 339 WP_013206421.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
PG903_RS05340 1099414..1099668 - 255 WP_013206420.1 type II toxin-antitoxin system HicA family toxin Toxin
PG903_RS05345 1099717..1102872 + 3156 WP_013206419.1 host specificity protein J -
PG903_RS05350 1103230..1103868 + 639 WP_013206417.1 hypothetical protein -
PG903_RS05355 1103937..1104428 + 492 WP_013206416.1 glycoside hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1070042..1118147 48105


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-75)

Antitoxin

Uncharacterised protein family HicB

(55-105)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 9442.01 Da        Isoelectric Point: 10.2487

>T267534 WP_013206420.1 NZ_CP115952:c1099668-1099414 [Ralstonia solanacearum CFBP2957]
MKAKHQKTLELIFSRPTPASVKWADAVALMKELGAELEEREGSRVAVFLFGQVKVMHRPHPSPDIDKGAVASMRKWFEEN
GVKP

Download         Length: 255 bp

Antitoxin


Download         Length: 113 a.a.        Molecular weight: 12092.73 Da        Isoelectric Point: 5.1462

>AT267534 WP_013206421.1 NZ_CP115952:c1099417-1099079 [Ralstonia solanacearum CFBP2957]
MINVMNIGGHKAVIAYDPDIEMFRGEFVGLNGGADFYAADVPGLHREGELSLRVFLDECARRGVEPQKHFSGRFVLRVEG
KVHEAAAIAAAARGVSLNQWAADVLEQAAEVA

Download         Length: 339 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References